Nagaoka H, Innami R, Arai H, Tonouchi S
Department of Cardiovascular Surgery, Tsuchiura Kyodo General Hospital, Japan.
Nihon Geka Gakkai Zasshi. 1988 Jul;89(7):1099-104.
The comparative studies on operative and hemodynamic results following aorto-coronary bypass grafting were performed in 9 patients with left main trunk (LMT) stenosis and 20 with left main equivalent (LME). One of 20 LME had bypass grafts occluded on the postoperative angiogram. There were two operative deaths, one in LMT, another in LME, and one late death. Following results were obtained in 8 LMT (Group I) and 15 LME (Group II) whose all bypass grafts were patent. There were significantly higher operative mortality rate and the incidence of perioperative myocardial infarction in Group I (11.1% versus 5.0%). Cardiac index and left ventricular ejection fraction significantly increased postoperatively in both groups. Mean Vcf and PLVSP/LVESV significantly increased postoperatively in Group II, but not in Group I. Left ventricular anterior segmental wall motion significantly increased in both groups and apical in Group I, whereas it did not in the postero-inferior segment. The completely revascularized patients had a better postoperative left ventricular function comparing with the incompletely revascularized patients. Angina disappeared postoperatively in all patients in Group I and 12 (75%) in Group II. In both groups, NYHA classification was improved from class III or IV preoperatively to class I or II postoperatively. Postoperative 8 years actuarial survival rate was 88.2% in Group I and 84.6% in Group II. In conclusion, it was suggested that much more strict perioperative management and complete revascularization were needed in the patient with LMT.
对9例左主干(LMT)狭窄患者和20例左主干等同病变(LME)患者进行了主动脉冠状动脉搭桥术后手术及血流动力学结果的比较研究。20例LME患者中有1例术后血管造影显示搭桥血管闭塞。有2例手术死亡,1例在LMT组,另1例在LME组,还有1例晚期死亡。8例LMT患者(I组)和15例LME患者(II组)的所有搭桥血管均通畅,获得了以下结果。I组的手术死亡率和围手术期心肌梗死发生率显著更高(分别为11.1%和5.0%)。两组术后心脏指数和左心室射血分数均显著增加。II组术后平均圆周纤维缩短率和左心室压力峰值/左心室舒张末期容积显著增加,而I组未增加。两组左心室前壁节段运动均显著增加,I组心尖部增加,而后下壁未增加。完全血运重建的患者与不完全血运重建的患者相比,术后左心室功能更好。I组所有患者术后心绞痛消失,II组12例(75%)患者术后心绞痛消失。两组患者纽约心脏协会(NYHA)分级均从术前的III级或IV级改善为术后的I级或II级。I组术后8年精算生存率为88.2%,II组为84.6%。总之,提示LMT患者需要更严格的围手术期管理和完全血运重建。