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经皮冠状动脉介入治疗后紧急心脏手术的全国评估及术后患者结局。

A National Evaluation of Emergency Cardiac Surgery After Percutaneous Coronary Intervention and Postsurgical Patient Outcomes.

机构信息

Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK; Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK.

Department of Cardiology, University College Hospital, London, UK.

出版信息

Am J Cardiol. 2020 Sep 1;130:24-29. doi: 10.1016/j.amjcard.2020.05.041. Epub 2020 Jun 7.

Abstract

There is limited national data regarding emergency cardiac surgery for complications sustained after percutaneous coronary intervention (PCI). This study aimed to examine emergency cardiac surgery after PCI in England and Wales and postsurgical patient outcomes. We analyzed patients in the British Cardiovascular Intervention Society database who underwent PCI between 2007 and 2014 and compared characteristics and outcomes for patients with and without emergency cardiac surgery. A total of 549,303 patients were included in the analysis and 362 (0.07%) underwent emergency cardiac surgery. There was a modest decline in the annual rate of emergency cardiac surgery from 0.09% to 0.06% between 2007 and 2014. Variables associated with emergency cardiac surgery included receipt of circulatory support (Odds ratio (OR) 39.20 95% confidence interval (CI) 27.75 to 55.36), aortic dissection (OR 28.39 95%CI 14.59 to 55.26), coronary dissection (OR 18.50 95%CI 13.60 to 25.18), coronary perforation (OR 7.86 95%CI 4.27 to 14.46), cardiac tamponade (OR 6.77 95%CI 3.13 to 14.66), and on-site surgical cover (OR 2.15 95%CI 1.56 to 2.97). After adjustments, patients with emergency cardiac surgery were at increased odds of 30-day mortality (OR 4.41 95%CI 2.94 to 6.62) and in-hospital major adverse cardiac and cerebrovascular events (OR 1.63 95%CI 1.07 to 2.48). On site surgical cover was independently associated with increased odds of mortality (OR 1.26 95%CI 1.20 to 1.33) following emergency cardiac surgery. In conclusion, emergency cardiac surgery after PCI is a rarely required procedure and in England and Wales there appears to be a decline in recent years. Patients who underwent emergency cardiac surgery have higher risk of adverse outcomes and longer length of hospital stay.

摘要

关于经皮冠状动脉介入治疗(PCI)后并发症导致的紧急心脏手术,全国数据有限。本研究旨在研究英格兰和威尔士的 PCI 后紧急心脏手术以及手术后患者的结局。我们分析了 2007 年至 2014 年间在英国心血管介入学会数据库中接受 PCI 的患者,并比较了有和没有紧急心脏手术的患者的特征和结局。共纳入 549303 例患者,其中 362 例(0.07%)行紧急心脏手术。2007 年至 2014 年,紧急心脏手术的年发生率从 0.09%适度下降至 0.06%。与紧急心脏手术相关的变量包括接受循环支持(比值比(OR)39.20,95%置信区间(CI)27.75 至 55.36)、主动脉夹层(OR 28.39,95%CI 14.59 至 55.26)、冠状动脉夹层(OR 18.50,95%CI 13.60 至 25.18)、冠状动脉穿孔(OR 7.86,95%CI 4.27 至 14.46)、心脏压塞(OR 6.77,95%CI 3.13 至 14.66)和现场手术覆盖(OR 2.15,95%CI 1.56 至 2.97)。调整后,行紧急心脏手术的患者 30 天死亡率(OR 4.41,95%CI 2.94 至 6.62)和住院期间主要心脏和脑血管不良事件(OR 1.63,95%CI 1.07 至 2.48)的可能性增加。现场手术覆盖与紧急心脏手术后死亡率(OR 1.26,95%CI 1.20 至 1.33)的增加独立相关。总之,PCI 后紧急心脏手术是一种很少需要的手术,在英格兰和威尔士,近年来这一手术的数量似乎有所下降。行紧急心脏手术的患者不良结局风险较高,住院时间较长。

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