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汤姆摄影乳腺 X 线成像筛查试验(TMIST):邀请和机会,让全国医学协会社区共同塑造未来乳腺癌精准筛查。

Tomosynthesis mammographic Imaging Screening Trial (TMIST): An Invitation and Opportunity for the National Medical Association Community to Shape the Future of Precision Screening for Breast Cancer.

机构信息

National Cancer Institute, Division of Cancer Prevention, Community Oncology and Prevention Trials Group, 9609 Medical Center Drive, Room 5E516 Rockville, MD 20850, USA.

National Cancer Institute, Division of Cancer Prevention, Community Oncology and Prevention Trials Group, 9609 Medical Center Drive, Room 5E516 Rockville, MD 20850, USA.

出版信息

J Natl Med Assoc. 2020 Dec;112(6):613-618. doi: 10.1016/j.jnma.2020.05.021. Epub 2020 Jul 9.

Abstract

To determine the best screening modality for breast cancer, a large randomized clinical trial is underway to compare the mammographic accuracy between the standard digital and tomosynthesis mammography. The Tomosynthesis Mammographic Imaging Screening Trial (TMIST) is also building the world's largest biorepository of breast cancer specimens from all biopsies at screening and wants to ensure it is representative of the US population. We invite the National Medical Association physicians, as leaders in the health care of African Americans, to continue their commitment to eliminating disparities by promoting the TMIST among African American women. The outcome of the trial will help to advance precision screening, individually tailoring screening decisions based on breast density, tumor subtyping and genomics. The partnership with NMA is essential to building trust, dispelling misconceptions about clinical trials in the community as well as to support a cadre of African American physicians and researchers who can contribute to the current understanding of the social determinants of breast cancer.

摘要

为了确定乳腺癌的最佳筛查方式,一项大型随机临床试验正在进行中,旨在比较标准数字乳腺摄影术和断层合成乳腺摄影术的乳腺摄影术准确性。断层合成乳腺摄影术筛查试验(TMIST)还在建立世界上最大的乳腺癌生物库,其中包括所有筛查活检的乳腺癌标本,并希望确保其能代表美国人口。我们邀请全国医学协会的医生作为非裔美国人医疗保健的领导者,通过在非裔美国女性中推广 TMIST,继续致力于消除差异。该试验的结果将有助于推进精准筛查,根据乳腺密度、肿瘤亚型和基因组学,为每个患者量身定制筛查决策。与 NMA 的合作对于建立信任、消除社区对临床试验的误解以及支持一批非裔美国医生和研究人员非常重要,他们可以为当前对乳腺癌社会决定因素的理解做出贡献。

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