Siemes H, Casaer P
Rittberg-Kinderklinik Berlin.
Monatsschr Kinderheilkd. 1988 Aug;136(8):467-70.
From 6 months of age on this girl experienced frequent episodes of hemiplegia involving both sides of the body and lasting up to 8 days. The attacks were often precipitated by tonic deviation of the head and/or the eyes to one side and nystagmus. At this stage the girl used to cry. Squinting, tonic stiffening of body and extremities, and dystonic posturing also occurred. Autonomic dysfunctions such as paleness of the skin, sweating, respiratory embarrassment, tachycardia, and mydriasis were associated features of the attacks. Motor and mental development of the girl is delayed. Improvement concerning severity, duration and frequency of the attacks has been achieved by permanent treatment with flunarizine in combination with acetazolamide and acetylsalicylic acid. If the child falls asleep immediately after rectal application of chloral hydrate at the onset of an attack there is no hemiplegia after awakening.
从6个月大起，这个女孩就频繁出现身体两侧的偏瘫发作，持续长达8天。发作常由头部和/或眼睛向一侧的强直性偏斜以及眼球震颤引发。在这个阶段，女孩常常会哭闹。还会出现斜视、身体和四肢的强直性僵硬以及张力障碍姿势。发作的相关特征还包括自主神经功能障碍，如皮肤苍白、出汗、呼吸窘迫、心动过速和瞳孔散大。女孩的运动和智力发育迟缓。通过使用氟桂利嗪联合乙酰唑胺和阿司匹林进行长期治疗，发作的严重程度、持续时间和频率都有所改善。如果在发作开始时直肠给予水合氯醛后孩子立即入睡，醒来后就不会出现偏瘫。
