Laboratory of Pathology, School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5201, Japan.
Laboratory of Small Animal Clinics, Veterinary Teaching Hospital, Azabu University, 1-17-71, Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5201, Japan.
J Vet Med Sci. 2020 Oct 7;82(9):1395-1399. doi: 10.1292/jvms.20-0244. Epub 2020 Jul 13.
A four-and-a-half-year-old female Scottish Fold cat underwent partial pancreatectomy with en-bloc splenectomy. The resected specimen was a biphasic tumor that was diagnosed histologically and immunohistochemically as pancreatic adenosquamous carcinoma (ASC), a ductal carcinoma variant according to the WHO classification of tumors in humans. There was a gradual transition between the adenocarcinoma component and the squamous cell carcinoma component. The squamous cell carcinoma component comprised approximately 30-40% of the tumor. A pancreatic tumor infiltrated into the gastrosplenic ligament and spleen with regional lymph node and mesenteric metastases. Pancreatic ASC has not been reported in animals. This is a case report of feline pancreatic ASC with splenic involvement.
一只四岁半的雌性苏格兰折耳猫接受了部分胰腺切除术和脾切除术。切除的标本为双相肿瘤，经组织学和免疫组织化学诊断为胰腺腺鳞癌（ASC），根据人类肿瘤 WHO 分类为导管癌的一种变体。腺癌成分和鳞状细胞癌成分之间有逐渐过渡。鳞状细胞癌成分约占肿瘤的 30-40%。胰腺肿瘤浸润胃脾韧带和脾脏，并伴有区域性淋巴结和肠系膜转移。动物的胰腺 ASC 尚未有报道。这是一例伴有脾脏受累的猫胰腺 ASC 的病例报告。
