Winsløw Frederik, Hansen Nadja Skadkær, Jensen Michael Broksgaard
Department of Neurology, North Zealand Hospital, Hillerød, Denmark.
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
J Cent Nerv Syst Dis. 2020 Jun 30;12:1179573520939340. doi: 10.1177/1179573520939340. eCollection 2020.
We report the case of a 37-year-old male patient with chronic amphetamine abuse who presented with vertebral artery dissection. Prior to presentation, he had increased the consumption of amphetamine from 5 times a year to once every week and had used amphetamine on the day of presentation. He attended with neck pain, vertigo and coordinating difficulties of his left arm. Computed tomography angiogram of the neck vessels showed a left vertebral stenosis and cerebral magnetic resonance imaging showed a left vertebral pseudolumen and a medullary stroke. Cervical artery dissection is a major cause of stroke in the young. To the authors' knowledge, this is the second reported case of vertebral artery dissection in a patient with amphetamine abuse. Amphetamine might contribute to an increased risk of vertebral artery dissection through its vasculopathic properties although more data are needed to establish a causal relationship.
我们报告了一例37岁慢性苯丙胺滥用男性患者,其出现了椎动脉夹层。在就诊前,他将苯丙胺的使用量从每年5次增加到每周1次,且在就诊当天使用了苯丙胺。他因颈部疼痛、眩晕和左臂协调困难前来就诊。颈部血管计算机断层血管造影显示左椎动脉狭窄,脑部磁共振成像显示左椎动脉假腔和延髓卒中。颈动脉夹层是年轻人中风的主要原因。据作者所知,这是第二例报告的苯丙胺滥用患者发生椎动脉夹层的病例。尽管需要更多数据来建立因果关系,但苯丙胺可能因其血管病变特性而增加椎动脉夹层的风险。