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颈动脉粥样硬化扩展:临床实践中的一个切入点

Atherosclerotic Extension of Carotid Arteries: An Insertion in Clinical Practice.

作者信息

Furlanetto M L, Chagas E F B, Slm Payão

机构信息

Faculdade de Medicina de Marília, Marília, São Paulo, Brazil.

出版信息

Int J Vasc Med. 2020 Jun 23;2020:3120327. doi: 10.1155/2020/3120327. eCollection 2020.

Abstract

INTRODUCTION

Atherosclerotic disease is a diffuse disease that is strongly associated with age, risk factors, and variable progression. The anatomical prevalence of atheromas does not always follow, a sequence by sectors, and in many cases are concomitant.

OBJECTIVES

This study is aimed at studying atherosclerosis in the arterial territories of the carotid and lower limbs, in order to correlate their extension as a form of primary prevention.

METHODS

Participating patients with the main risk factors for atherosclerotic disease were composed of two groups: one with chronic peripheral obstructive arterial disease (PAD) and another without PAD. After performing carotid ultrasound Doppler (USD) of all patients, the occasional prevalence of the disease was evaluated. We performed by statistical tests the correlation between the findings in these patients and the risk factors. Obtaining from 226 patients, in which 116 patients are from the PAD group and 110 patients are from the group without PAD.

RESULTS

Our findings add up to 8.8% for lesions over 50% in patients with PAD, with 6.2% over 70% meeting the few published scientific findings. In this study, the correlation was evaluated between carotid stenosis and PAD, in which we observed a positive association. We observed in the studies that the prevalence of moderate and severe carotid stenosis was similar to patients with coronary artery disease (CAD). There are a number of nonclassical risk factors that we do not evaluate, but even studying the traditional ones, we find that they are less than 27% dependent.

CONCLUSION

Therefore, our study proposes an improvement in the clinical approach of patients with PAD for both the carotid and coronary territory, not using only 2 factors traditional risk factors, for the extension study and to consider the PAD that has 10% dependence alone, as effect and projection of the carotid atherosclerotic plaque.

摘要

引言

动脉粥样硬化疾病是一种弥漫性疾病,与年龄、危险因素及可变的病情进展密切相关。动脉粥样硬化斑块的解剖学分布并不总是按节段顺序出现,在很多情况下是同时存在的。

目的

本研究旨在研究颈动脉和下肢动脉区域的动脉粥样硬化情况,以便将其病变范围作为一级预防的一种形式进行关联分析。

方法

纳入具有动脉粥样硬化疾病主要危险因素的患者,分为两组:一组为慢性外周动脉阻塞性疾病(PAD)患者,另一组为无PAD患者。对所有患者进行颈动脉超声多普勒(USD)检查后,评估该疾病的偶发患病率。我们通过统计检验分析这些患者的检查结果与危险因素之间的相关性。共纳入226例患者,其中116例来自PAD组,110例来自无PAD组。

结果

我们的研究结果显示,PAD患者中病变超过50%的比例总计为8.8%,超过70%的比例为6.2%,这与少数已发表的科学研究结果相符。在本研究中,对颈动脉狭窄与PAD之间的相关性进行了评估,我们观察到二者呈正相关。我们在研究中发现,中度和重度颈动脉狭窄的患病率与冠心病(CAD)患者相似。有一些非经典危险因素我们未进行评估,但即使仅研究传统危险因素,我们发现它们的依赖性也不到27%。

结论

因此,我们的研究建议改进PAD患者在颈动脉和冠状动脉区域的临床治疗方法,不仅要考虑2个传统危险因素,还应进行病变范围研究,并将单独具有10%依赖性的PAD视为颈动脉粥样硬化斑块的影响和表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d855/7330634/b4b25bc26554/IJVM2020-3120327.001.jpg

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