Osama Muhammad, Khan Anosh Aslam, Syed Sohaib Hasan, Mohiuddin Osama, Hassan Ammar, Zaidi Syeda Ramsha, Sami Neelofar
General Surgery, Dow University of Health Sciences, Karachi, PAK.
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus. 2020 Jun 8;12(6):e8507. doi: 10.7759/cureus.8507.
Background The prevalence of chronic malnutrition and its associated morbid outcomes has been a significant cause of health loss globally, affecting millions of children hampering their mental, physical, social, and immune system development. World Health Organization's (WHO) recommendations presenting infant feeding guidelines have largely controlled this burden. However, developing countries including Pakistan have failed to promote these guidelines and still succumb to a huge burden of morbidity and mortality secondary to malnourishment among infants. Methodology Our study is a prospective cohort including 300 infants without predisposing congenital anomaly, followed from 6 months to 18 months of age. The primary outcome involved was classifying patients as malnourished based on anthropometric measurements, assessing the prevalence of co-morbidities and comparison of results in compliance with WHO guidelines. Results A total of 276 infants were included and the rest were lost to follow-up. Stratification on socioeconomic status was done; 53% of infants were diagnosed as malnourished, either due to stunted growth, underweight, or both. The odds of development of malnourishment based on non-adherence to WHO guidelines on breastfeeding were 2.87 (p=0.001). The incidence of morbid complications was higher in the malnourished group, including gastrointestinal and respiratory tract infections. Conclusion The implementation of WHO recommendations on infant feeding techniques can prove to be a pivotal instrument to control the soaring index of morbidities and mortalities associated with malnourishment. A strong focus on parental education and awareness among masses is required for its promulgation and controlling the infant health burden linked to this preventable condition.
慢性营养不良及其相关的不良后果在全球范围内一直是导致健康损失的重要原因,影响着数百万儿童,阻碍他们的心理、身体、社交和免疫系统发育。世界卫生组织(WHO)提出的婴儿喂养指南在很大程度上控制了这一负担。然而,包括巴基斯坦在内的发展中国家未能推广这些指南,婴儿仍因营养不良而承受着巨大的发病和死亡负担。
我们的研究是一项前瞻性队列研究,纳入300名无先天性异常易患因素的婴儿,随访时间为6个月至18个月。主要结果包括根据人体测量将患者分类为营养不良,评估合并症的患病率,并将结果与WHO指南进行比较。
共纳入276名婴儿,其余失访。按社会经济地位进行分层;53%的婴儿被诊断为营养不良,原因是生长发育迟缓、体重不足或两者皆有。基于不遵守WHO母乳喂养指南而发生营养不良的几率为2.87(p = 0.001)。营养不良组的发病并发症发生率更高,包括胃肠道和呼吸道感染。
实施WHO关于婴儿喂养技术的建议可证明是控制与营养不良相关的发病率和死亡率飙升指数的关键手段。为了推广该建议并控制与这种可预防疾病相关的婴儿健康负担,需要大力关注对父母的教育和提高大众的认识。