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引用本文的文献

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Effects of synthetic cannabinoids on psychomotor, sensory and cognitive functions relevant for safe driving.合成大麻素对与安全驾驶相关的精神运动、感觉和认知功能的影响。
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本文引用的文献

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What are the psychological effects of using synthetic cannabinoids? A systematic review.使用合成大麻素的心理影响有哪些？一项系统综述。
J Psychopharmacol. 2019 Mar;33(3):271-283. doi: 10.1177/0269881119826592. Epub 2019 Feb 21.
2
Can Long-Term Regular Practice of Physical Exercises Including Taichi Improve Finger Tapping of Patients Presenting With Mild Cognitive Impairment?长期定期进行包括太极拳在内的体育锻炼能否改善轻度认知障碍患者的手指敲击能力？
Front Physiol. 2018 Sep 28;9:1396. doi: 10.3389/fphys.2018.01396. eCollection 2018.
3
The Effects of Cannabinoids on Executive Functions: Evidence from Cannabis and Synthetic Cannabinoids-A Systematic Review.大麻素对执行功能的影响：来自大麻和合成大麻素的证据——一项系统综述。
Brain Sci. 2018 Feb 27;8(3):40. doi: 10.3390/brainsci8030040.
4
Evaluation of cognitive functions in individuals with synthetic cannabinoid use disorder and comparison to individuals with cannabis use disorder.评估合成大麻素使用障碍个体的认知功能，并与大麻使用障碍个体进行比较。
Psychiatry Res. 2018 Apr;262:46-54. doi: 10.1016/j.psychres.2018.01.046. Epub 2018 Jan 31.
5
Altered cortical maturation in adolescent cannabis users with and without schizophrenia.有或无精神分裂症的青少年大麻使用者的皮质成熟改变。
Schizophr Res. 2015 Mar;162(1-3):143-52. doi: 10.1016/j.schres.2014.11.029. Epub 2015 Jan 15.
6
Use of computerized tests to evaluate psychomotor performance in children with specific learning disabilities in comparison to normal children.与正常儿童相比，使用计算机化测试评估特定学习障碍儿童的心理运动表现。
Indian J Med Res. 2014 Nov;140(5):644-8.
7
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.合成大麻素：流行病学、药效学及临床意义。
Drug Alcohol Depend. 2014 Nov 1;144:12-41. doi: 10.1016/j.drugalcdep.2014.08.005. Epub 2014 Aug 18.
8
Protein kinase B (AKT1) genotype mediates sensitivity to cannabis-induced impairments in psychomotor control.蛋白激酶 B（AKT1）基因型介导大麻引起的运动控制障碍的敏感性。
Psychol Med. 2014 Nov;44(15):3315-28. doi: 10.1017/S0033291714000920. Epub 2014 Apr 29.
9
Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death.合成大麻素对大脑前体细胞的细胞毒性：大麻素 CB1 受体和细胞凋亡的参与。
Toxicol Appl Pharmacol. 2014 Jan 1;274(1):17-23. doi: 10.1016/j.taap.2013.10.028. Epub 2013 Nov 6.
10
Bimanual motor deficits in older adults predicted by diffusion tensor imaging metrics of corpus callosum subregions.通过胼胝体亚区域的扩散张量成像指标预测老年人的双手运动功能障碍。
Brain Struct Funct. 2015 Jan;220(1):273-90. doi: 10.1007/s00429-013-0654-z. Epub 2013 Oct 26.

至少两年使用合成大麻素对寻求治疗的男性门诊患者认知和心理运动功能的影响。

Impact of At Least 2 Years of Synthetic Cannabinoid Use on Cognitive and Psychomotor Functions Among Treatment-Seeking Male Outpatients.

作者信息

Umut Gokhan, Evren Cuneyt, Atagun Murat Ilhan, Hisim Ozge, Yilmaz Cengel Hanife, Bozkurt Muge, Keskinkilic Cahit

机构信息

Research, Treatment and Training Center for Alcohol and Substance Dependence (AMATEM), Bakirkoy Training and Research Hospital for Psychiatry Neurology and Neurosurgery, Istanbul, Turkey.

Department of Psychiatry, Medicine Faculty, Yildirim Beyazit University, Ankara, Turkey.

出版信息

Cannabis Cannabinoid Res. 2020 Jun 5;5(2):164-171. doi: 10.1089/can.2019.0017. eCollection 2020 Jun 1.

DOI:10.1089/can.2019.0017
PMID:32656348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7347054/
Abstract

Synthetic cannabinoid (SC) use, an important public health problem, is becoming increasingly widespread and leads to many medical and psychiatric problems. This study aimed to evaluate the impact of SC use on cognitive and psychomotor functions of patients. The participants (30 outpatients with SC use disorder and 33 healthy controls) were administered the Montreal Cognitive Assessment (MOCA) test, the Edinburgh Handedness Inventory (EHI), the Finger-Tapping Test (FTT), and the Adult Memory and Information Processing Battery-B form (AMIPB-B). The SC users scored lower in AMIPB-B, MOCA. and FTT compared to the healthy controls. These findings suggest that SC might impair both cognitive and psychomotor functions. Therefore, outpatients with SC use disorder should be carefully evaluated for cognitive and psychomotor functions since neurological examinations and interventions may also be required in treatment programs for these cases.

摘要

合成大麻素（SC）的使用是一个重要的公共卫生问题，且日益普遍，并导致诸多医学和精神问题。本研究旨在评估使用SC对患者认知和心理运动功能的影响。参与者（30名患有SC使用障碍的门诊患者和33名健康对照者）接受了蒙特利尔认知评估（MOCA）测试、爱丁堡利手量表（EHI）、手指敲击测试（FTT）以及成人记忆与信息处理成套测验-B型（AMIPB-B）。与健康对照者相比，使用SC的患者在AMIPB-B、MOCA和FTT测试中的得分较低。这些发现表明，SC可能损害认知和心理运动功能。因此，对于患有SC使用障碍的门诊患者，应仔细评估其认知和心理运动功能，因为在这些病例的治疗方案中可能还需要进行神经学检查和干预。