Research, Treatment and Training Center for Alcohol and Substance Dependence (AMATEM), Bakirkoy Training and Research Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey.
Research, Treatment and Training Center for Alcohol and Substance Dependence (AMATEM), Bakirkoy Training and Research Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey.
Psychiatry Res. 2018 Apr;262:46-54. doi: 10.1016/j.psychres.2018.01.046. Epub 2018 Jan 31.
The use of synthetic cannabinoid has been increasing throughout the world and has become a major public health problem. The present study aims to investigate the attention, memory, visuospatial and executive functions in individuals with synthetic cannabinoid use disorder and compare the results with findings obtained from individuals with cannabis use disorder and healthy volunteers with no substance use. Fifty-two patients with synthetic cannabinoid use disorder, 45 patients with cannabis use disorder and 48 healthy control group males were included in the study. The neuropsychological test battery was designed to involve ten studies evaluating a large series of cognitive functions. Impairments in attention, memory, executive and visuospatial functions were identified in individuals with synthetic cannabinoid use disorder and these impairments were found to be significantly greater than in individuals with cannabis use disorder and healthy controls. In line with the data obtained from this study; the evaluation of each cognitive function with more comprehensive test batteries and supporting these evaluations with sensitive brain imaging studies are important topics for future research.
合成大麻素的使用在全球范围内不断增加，已成为一个主要的公共卫生问题。本研究旨在调查合成大麻素使用障碍个体的注意力、记忆、视空间和执行功能，并将结果与大麻使用障碍个体和无物质使用的健康志愿者的发现进行比较。本研究纳入了 52 名合成大麻素使用障碍患者、45 名大麻使用障碍患者和 48 名健康男性对照组。神经心理学测试组合旨在进行十项研究，评估一系列广泛的认知功能。研究发现，合成大麻素使用障碍个体存在注意力、记忆、执行和视空间功能障碍，这些障碍明显大于大麻使用障碍个体和健康对照组。根据本研究获得的数据，使用更全面的测试组合评估每个认知功能，并通过敏感的脑成像研究支持这些评估，是未来研究的重要课题。
