Thakur Arpita, Niranjan Vijay, Rastogi Pali, Razdan Ramghulam
Department of Psychiatry, Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh, India.
Department of Psychiatry, MGM Medical College Indore, Indore, Madhya Pradesh, India.
Gen Psychiatr. 2020 Jul 1;33(4):e100203. doi: 10.1136/gpsych-2020-100203. eCollection 2020.
Risperidone acts by potent serotonergic, dopaminergic and alpha adrenergic receptor antagonism. The most common side effects reported are extrapyramidal symptoms, dizziness, sedation, insomnia, headache, anxiety, nausea, constipation and weight gain. Oedema associated with risperidone use is a rare side effect. Here we present a report on pedal oedema associated with use of oral risperidone 4 mg per day for acute-onset psychotic illness. Through this case report we want to make clinicians aware about this important side effect as it can affect patients' compliance and quality of life.
利培酮通过强效的5-羟色胺能、多巴胺能和α-肾上腺素能受体拮抗作用发挥功效。报告的最常见副作用为锥体外系症状、头晕、镇静、失眠、头痛、焦虑、恶心、便秘和体重增加。与使用利培酮相关的水肿是一种罕见的副作用。在此，我们报告一例因每日口服4毫克利培酮治疗急性起病的精神病性疾病而导致足背水肿的病例。通过本病例报告，我们希望让临床医生意识到这一重要副作用，因为它可能影响患者的依从性和生活质量。
