Faculty of Science, Department of Organic Chemistry, University of Yaoundé 1, Yaoundé, Cameroon.
Center for Studies on Medicinal Plants and Traditional Medicine (CRPMT), Institute of Medical Research and Medicinal Plants Studies (IMPM), Yaoundé, Cameroon.
Nat Prod Res. 2021 Dec;35(23):5535-5539. doi: 10.1080/14786419.2020.1793147. Epub 2020 Jul 13.
The methanolic extract of the waste seeds of L. (Pedaliaceae) was subjected to chromatographic fractionation; it led to the isolation of an alkyl benzene identified as 1,3-bis (pentadecyl)benzene () along with three known fatty acids: oleic acid (), linoleic acid (), and palmitic acid (); one monosaturated cardanol, 3-pentadecylphenol () and two phytosteroids identified as sitostanol () and campestanol (). The structures of these compounds were elucidated by chemical and spectroscopic analyses. Compounds , and were evaluated against protozoan parasites. Compound moderately inhibited the promastigote form of LG13 with IC equal to 16.9 μM.
L.（旋花科）废弃种子的甲醇提取物经色谱分离；从中分离得到一种烷基苯，鉴定为 1,3-双（十五烷基）苯（），以及三种已知脂肪酸：油酸（）、亚油酸（）和棕榈酸（）；一种单不饱和卡醇，3-十五烷基苯酚（）和两种植物甾醇，鉴定为谷甾醇（）和菜油甾醇（）。这些化合物的结构通过化学和光谱分析得到阐明。化合物、和 对原生动物寄生虫进行了评估。化合物 对 LG13 的前鞭毛体形式具有中等抑制作用，IC 为 16.9 μM。
