脑脊液细胞中的α-萘乙酸酯酶活性

Alpha-naphthyl-acetate-esterase activity in cerebrospinal fluid cells.

作者信息

De Reuck J, Vanderdonckt P

机构信息

Department of Neurology, University Hospital, Gent, Belgium.

出版信息

Acta Neurol Scand. 1988 Sep;78(3):190-3. doi: 10.1111/j.1600-0404.1988.tb03644.x.

DOI:10.1111/j.1600-0404.1988.tb03644.x

PMID:3265833

Abstract

Mono-histiocytes and T-lymphocytes were assessed by the cytochemical alpha-naphthyl-acetate-esterase (ANAE) stain in 50 CSF samples of patients with various neurological diseases. The ANAE-activity of lymphocytes was decreased in multiple sclerosis and subacute sclerosing panencephalitis, while the activity of mono-histiocytes was increased in the group of infarctions and bacterial and viral infections of the central nervous system. In bacterial meningitis and viral meningo-encephalo-radiculitis the number of ANAE-positive lymphocytes increased after treatment and clinical improvement. ANAE staining appears to be a useful additional tool in CSF cytology in these conditions.

摘要

采用细胞化学α-萘乙酸酯酶（ANAE）染色法，对50例患有各种神经系统疾病患者的脑脊液样本中的单核组织细胞和T淋巴细胞进行了评估。在多发性硬化症和亚急性硬化性全脑炎中，淋巴细胞的ANAE活性降低，而在梗死组以及中枢神经系统细菌和病毒感染组中，单核组织细胞的活性增加。在细菌性脑膜炎和病毒性脑膜脑神经根炎中，治疗后及临床症状改善后，ANAE阳性淋巴细胞数量增加。在这些情况下，ANAE染色似乎是脑脊液细胞学检查中一种有用的辅助手段。