Peyman G A, Charles H C, Liu K R, Khoobehi B, Niesman M
LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans.
Int Ophthalmol. 1988;12(3):175-82. doi: 10.1007/BF00130002.
Intravitreal liposome-encapsulated antibiotics and antiviral drugs were used in patients with acute toxoplasmosis retinochoroiditis, presumed propionibacterium acne endophthalmitis after cataract surgery, and presumed cytomegalovirus retinitis associated with AIDS. A single intravitreal dose was effective in the treatment of all the conditions. Intravitreal liposomes may prove to be an advantageous drug delivery system for the treatment of chronic intraocular inflammatory disorders.
玻璃体内注射脂质体包裹的抗生素和抗病毒药物被用于患有急性弓形虫性视网膜脉络膜炎、白内障手术后疑似痤疮丙酸杆菌性眼内炎以及与艾滋病相关的疑似巨细胞病毒性视网膜炎的患者。单次玻璃体内给药对所有这些病症的治疗均有效。玻璃体内脂质体可能被证明是治疗慢性眼内炎性疾病的一种有利的药物递送系统。
