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分娩时的新型冠状病毒2型感染检测:临床和流行病学重点

SARS-CoV-2 infection testing at delivery: a clinical and epidemiological priority.

作者信息

Ferrazzi Enrico, Beretta Paolo, Bianchi Stefano, Cetin Irene, Guarnerio Paolo, Locatelli Anna, Marconi Anna Maria, Meroni Mario Giuseppe, Pavone Giulia, Pintucci Armando, Prefumo Federico, Savasi Valeria, Spinillo Arsenio, Tassis Beatrice, Vergani Patrizia, Vignali Michele, Parazzini Fabio, La Vecchia Carlo

机构信息

Department of Mother, Child and Neonate, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

出版信息

J Matern Fetal Neonatal Med. 2022 Jun;35(12):2417-2419. doi: 10.1080/14767058.2020.1788532. Epub 2020 Jul 13.

Abstract

BACKGROUND

Universal testing has been suggested as a useful strategy for a safe exit from the total lockdown, without recurrence of COVID-19 epidemic, delivering women being considered a sentinel population. Further universal testing for pregnant women may be useful in order to define appropriate access to COVID19 areas, dedicated neonatal care, and personal protective equipment.

METHODS

During the period 10-26 April, all consecutive women admitted for delivery at the Maternity Hospitals of the city of Milan and in six provinces of Lombardy: Brescia, Como, Lecco Monza, Pavia, and Sondrio. areas were tested with nasopharyngeal swabs. Out of 1566 women, 49 were tested positive for SARS-Cov-2 (3.1%, 95% Confidence Interval (CI) 2.3-4.0). This value is largely higher than Heath Authorities estimate. Of tested positive women, 22 (44.9%) had symptoms or reported close contacts with positive patients, that is were found at risk by the itemized questionnaire. In conclusion, routine estimate of frequency of positivity among delivering women can be consider a useful methods to monitor positivity at least in females in their fertile ages.

摘要

背景

普遍检测被认为是安全解除全面封锁、防止新冠疫情复发的一项有用策略,分娩女性被视为一个哨点人群。对孕妇进行进一步的普遍检测,可能有助于确定进入新冠区域、获得专门的新生儿护理以及个人防护装备的适当途径。

方法

在4月10日至26日期间,对米兰市及伦巴第大区六个省份(布雷西亚、科莫、莱科、蒙扎、帕维亚和松德里奥)的妇产医院所有连续入院分娩的女性进行检测。采集鼻咽拭子进行检测。在1566名女性中,49人新冠病毒检测呈阳性(3.1%,95%置信区间[CI] 2.3 - 4.0)。这一数值远高于卫生当局的估计。在检测呈阳性的女性中,22人(44.9%)有症状或报告与阳性患者有密切接触,即通过详细问卷被认定为有风险。总之,对分娩女性中阳性率的常规评估可被视为至少监测育龄女性阳性情况的一种有用方法。

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