Suppr超能文献

应用 AngioJet 经导管抽吸血栓清除术的过滤辅助腔静脉血栓形成猪模型

A Swine Model of Filter-Assisted Caval Thrombosis for Endovascular Thrombectomy Using AngioJet.

机构信息

Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.

Department of Vascular and Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

出版信息

J Cardiovasc Transl Res. 2021 Apr;14(2):365-370. doi: 10.1007/s12265-020-10059-8. Epub 2020 Jul 13.

Abstract

To assess the feasibility of creating swine model of filter-assisted caval thrombosis and to evaluate the efficacy in removing clot in this model using rheolytic thrombectomy. The model was created by implanting a filter into the inferior vena cava followed by injection of autologous thrombus. Rheolytic thrombectomy was performed for all models to remove the clot. The success rate of model creation and the efficacy of clot removal were analyzed. The success rate of model creation was 100% (15/15). Following rheolytic thrombectomy, 3 of 5 pigs attained complete clot removal in a 7-day-old model, while no pigs attained complete clot removal in 14- and 21-day-old models. Creating a filter-related caval thrombosis model in swine is technically feasible and can be used to mimic a clinical episode of caval thrombosis from acute phase to chronic occlusion. Rheolytic thrombectomy can be used to remove filter-related thrombosis that aged less than 14 days. Graphical Abstract Swine Model of Filter-Assisted Caval Thrombotic Occlusion.

摘要

评估建立滤器辅助性下腔静脉血栓形成猪模型的可行性,并评价应用旋切取栓术在该模型中清除血栓的效果。通过在下腔静脉中植入滤器,然后注入自体血栓来建立模型。对所有模型均进行旋切取栓术以清除血栓。分析模型建立的成功率和血栓清除的效果。模型建立的成功率为 100%(15/15)。在旋切取栓术后,7 天龄模型中有 3 只猪完全清除了血栓,而在 14 天和 21 天龄模型中没有猪完全清除血栓。在猪中建立滤器相关下腔静脉血栓形成模型在技术上是可行的,可用于模拟从急性期到慢性闭塞的临床下腔静脉血栓形成事件。旋切取栓术可用于清除年龄小于 14 天的滤器相关血栓。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验