Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital , Jena, Germany.
Expert Rev Anti Infect Ther. 2020 Dec;18(12):1235-1243. doi: 10.1080/14787210.2020.1794813. Epub 2020 Jul 26.
As sepsis is a life-threatening disease, appropriate measures should be started as soon as possible after diagnosis. Duration until first therapy affects survival. However, guideline adherence of primary sepsis care is often low. Dedicated sepsis response teams (SRT) may improve primary sepsis care.
PubMed was searched for studies investigating the effect of an implementation of SRTs. This review discusses the results of five studies presenting results before and after implementation of SRTs. The importance of choosing the alert and the right team composition of the SRT is also discussed.
Implementing SRTs is associated with a better compliance with guidelines regarding primary sepsis care and with a reduction in hospital mortality. However, scientific evidence of the studies is limited due to chosen study design. SRTs can be a strong method to improve primary sepsis care in specific hospital settings if the pros and cons against the other measures of quality improvement are considered and the technical details such as alerts and team members are customized to the individual hospital setting.
由于脓毒症是一种危及生命的疾病，因此在诊断后应尽快采取适当的措施。开始治疗的时间会影响患者的生存。然而，初级脓毒症治疗的指南遵循率往往较低。专门的脓毒症反应小组（SRT）可以改善初级脓毒症的治疗。
在 PubMed 上搜索了研究 SRT 对脓毒症治疗效果的影响的研究。这篇综述讨论了五项研究的结果，这些研究在实施 SRT 前后都呈现了结果。同时还讨论了选择警报和 SRT 合适团队组成的重要性。
实施 SRT 与更好地遵循初级脓毒症治疗指南以及降低医院死亡率相关。然而，由于研究设计的选择，研究的科学证据有限。如果考虑到与其他质量改进措施的利弊，并根据医院的具体情况对警报和团队成员等技术细节进行定制，那么 SRT 可以成为改善特定医院环境下初级脓毒症治疗的有力方法。
