Chen Da-Yin, Guo Ying-Xue, Dong Long-Xin, He Wen-Jie, Cao Hui-Feng, Wang Ping, Yue Cai-Fang
Department of Urology, The First Affiliated Hospital of Jiamusi University.
Department of Pharmacy, Jiamusi University.
Medicine (Baltimore). 2020 Jul 10;99(28):e21088. doi: 10.1097/MD.0000000000021088.
This study will examine the effectiveness and safety of neuromuscular electrical stimulation (NMES) for the treatment of patients with interstitial cystitis (IC).
We will retrieve the following electronic databases from their commencements to the March 1, 2020 to discover all related potential studies: MEDLINE, EMBASE, Cochrane Library, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and WANFANG Database. Randomized controlled trials related to the NMES for the treatment of patients with IC will be included, regardless publication status and language. Literature selection, data collection, and study quality assessment will be independently performed by 2 authors. The extracted data will be expressed as risk ratio and 95% confidence intervals for dichotomous data, and mean difference or standard mean difference and 95% confidence intervals for continuous data. RevMan V.5.3 software will be employed for statistical analysis.
This study will summarize current high quality randomized controlled trials to appraise the effectiveness and safety of NMES for the treatment of patients with IC.
The findings of this study will provide helpful evidence to determine whether NMES is an effective treatment for patients with IC or not.
PROSPERO CRD42020170495.
本研究将探讨神经肌肉电刺激（NMES）治疗间质性膀胱炎（IC）患者的有效性和安全性。
我们将检索以下电子数据库自建库起至2020年3月1日的所有相关潜在研究：医学文献数据库（MEDLINE）、荷兰医学文摘数据库（EMBASE）、考克兰图书馆、科学引文索引数据库（Web of Science）、护理学与健康照护领域累积索引数据库（CINAHL）、中国知网、中国生物医学文献数据库、中文科技期刊数据库和万方数据库。纳入所有与NMES治疗IC患者相关的随机对照试验，无论其发表状态和语言。文献筛选、数据收集和研究质量评估将由两位作者独立进行。提取的数据将以风险比和95%置信区间表示二分数据，以均值差或标准化均值差和95%置信区间表示连续数据。将使用RevMan V.5.3软件进行统计分析。
本研究将总结当前高质量随机对照试验，以评估NMES治疗IC患者的有效性和安全性。
本研究结果将为确定NMES是否为IC患者的有效治疗方法提供有益证据。
国际前瞻性系统评价注册库（PROSPERO）CRD42020170495。
