氢化可的松、硫胺素和维生素C对脓毒症或脓毒性休克患者有益吗？现在下结论还为时过早。 - Suppr

Benefit of hydrocortisone, thiamine, and vitamin C for patients with sepsis or septic shock? Too early to draw conclusions.

作者信息

Shi Rui, Tie Hongtao

机构信息

Service de Médecine Intensive - Réanimation, Hôpital Bicêtre, AP-HP, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

INSERM UMR_S999 LabEx - LERMIT, Hôpital Marie-Lannelongue, Le Plessis Robinson, France.

出版信息

Crit Care. 2020 Jul 14;24(1):431. doi: 10.1186/s13054-020-03153-5.

DOI:10.1186/s13054-020-03153-5

PMID:32665029

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7359457/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15fc/7359457/68073b265f9e/13054_2020_3153_Fig1_HTML.jpg

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Benefit of hydrocortisone, thiamine, and vitamin C for patients with sepsis or septic shock? Too early to draw conclusions.氢化可的松、硫胺素和维生素C对脓毒症或脓毒性休克患者有益吗？现在下结论还为时过早。

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The Efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients: a systematic review and meta-analysis.维生素C、硫胺素和皮质类固醇疗法对成年脓毒症患者的疗效：一项系统评价和荟萃分析。

Acute Crit Care. 2021 Aug;36(3):185-200. doi: 10.4266/acc.2021.00108. Epub 2021 Jun 30.

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Intern Emerg Med. 2021 Sep;16(6):1649-1661. doi: 10.1007/s11739-021-02735-7. Epub 2021 Apr 22.

本文引用的文献

JAMA. 2020 Feb 4;323(5):423-431. doi: 10.1001/jama.2019.22176.

Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis. Focus on Ascorbic Acid.氢化可的松、抗坏血酸和硫胺素（HAT 治疗）治疗败血症。重点关注抗坏血酸。

Nutrients. 2018 Nov 14;10(11):1762. doi: 10.3390/nu10111762.

Hydrocortisone in septic shock: all the questions answered?氢化可的松用于感染性休克：所有问题都有答案了吗？

J Thorac Dis. 2018 Jun;10(Suppl 17):S1962-S1965. doi: 10.21037/jtd.2018.04.120.

Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis.小剂量皮质类固醇治疗成人感染性休克患者：系统评价与荟萃分析及试验序贯分析。

Intensive Care Med. 2018 Jul;44(7):1003-1016. doi: 10.1007/s00134-018-5197-6. Epub 2018 May 14.

Chest. 2017 Jun;151(6):1229-1238. doi: 10.1016/j.chest.2016.11.036. Epub 2016 Dec 6.

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.系统评价与Meta分析的首选报告项目：PRISMA声明。

Ann Intern Med. 2009 Aug 18;151(4):264-9, W64. doi: 10.7326/0003-4819-151-4-200908180-00135. Epub 2009 Jul 20.

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Benefit of hydrocortisone, thiamine, and vitamin C for patients with sepsis or septic shock? Too early to draw conclusions.

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