The University of Buckingham, Buckingham, Buckinghamshire, UK.
National Spinal Injuries Centre, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK.
Spinal Cord Ser Cases. 2020 Jul 14;6(1):63. doi: 10.1038/s41394-020-0313-6.
Retrospective secondary analysis with a quantitative, matched-pairs design. Patients isolated due to methicillin-Resistant Staphylococcus aureus (MRSA) were matched with controls without MRSA infection admitted to a multi-bedded ward, based on: gender, injury level, injury severity (AIS grade), age at the time of injury and year of admission.
Determine the implications of MRSA-related infection isolation on spinal cord injury patients' anxiety, depression, appraisals of disability, perceived manageability and pain intensity. Hypotheses predicted patients who were isolated due to MRSA during inpatient stay would demonstrate poorer psychological health outcomes at discharge in comparison with non-isolated matched controls.
National Spinal Injuries Centre, England, UK.
Secondary analyses were conducted on pre-existing data based on patients' first admission for primary rehabilitation. Psychometric scales were used to measure outcome variables. Assessments were repeated at the time of admission and discharge.
Nonparametric longitudinal analyses using the nparLD package in R were conducted. Relative treatment effects demonstrated that there were no significant differences between groups across all outcome measures. There was a significant effect of time (admission vs discharge) on perceived manageability and pain intensity, indicating improved outcomes at discharge. There was no difference in the overall length of stay between the isolated and non-isolated groups.
Isolation experienced by rehabilitation inpatients with spinal cord injury with MRSA had no effect on a series of psychological outcomes. Engaging with rehabilitation had a positive impact in reducing pain unpleasantness and increasing perceived manageability of spinal cord injury, irrespective of infection isolation.
回顾性二次分析，采用定量、配对设计。根据性别、损伤水平、损伤严重程度（AIS 分级）、受伤时的年龄和入院年份，将因耐甲氧西林金黄色葡萄球菌（MRSA）而被隔离的患者与入住多床病房、无 MRSA 感染的对照患者进行配对。
确定与 MRSA 相关的感染隔离对脊髓损伤患者的焦虑、抑郁、残疾评估、可管理性感知和疼痛强度的影响。假设预测在住院期间因 MRSA 而被隔离的患者在出院时的心理健康状况会比未被隔离的匹配对照组差。
英国英格兰国家脊髓损伤中心。
对基于患者首次接受原发性康复治疗的首次入院的预先存在的数据进行二次分析。使用心理计量量表来测量结果变量。在入院时和出院时进行评估。
使用 R 中的 nparLD 包进行非参数纵向分析。相对治疗效果表明，在所有结果测量中，两组之间没有显著差异。可管理性和疼痛强度的入院与出院时间存在显著影响，表明出院时的结果有所改善。隔离组和非隔离组的总住院时间无差异。
脊髓损伤伴有耐甲氧西林金黄色葡萄球菌的康复住院患者的隔离对一系列心理结果没有影响。无论是否存在感染隔离，参与康复都能积极减轻疼痛不适，并增加对脊髓损伤的可管理性。
