Chandran Vennila, Ramanarayanan Venkitachalam, Menon Medhini, Varma Balagopal, Sanjeevan Vinita
Department of Pedodontics and Preventive Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
J Clin Exp Dent. 2020 Jun 1;12(6):e588-e596. doi: 10.4317/jced.56436. eCollection 2020 Jun.
To systematically review the effectiveness primary molar pulpotomy based on the clinical and radiographic outcomes using lasers over the conventional therapies.
This systematic review and meta-analysis included Randomized or Quasi-randomized trials comparing LASER with conventional pulpotomy therapies (formocresol, ferric sulphate, MTA or calcium hydroxide) with atleast 6-month follow-up period was included. Risk of bias of included studies was assessed and metanalysis was done using RevMan software.
Of the 1383 articles that were searched, only 14 studies were included for qualitative synthesis and 10 for meta- analysis. There was no statistically significant difference in clinical success rate [OR 0.99, 95%CI (0.19,5.22)] or radiographic success rate [OR 0.77, 95%CI (0.31,1.87)] of LASER therapy compared to Formocresol in primary molar pulpotomy for 6 months. No statistically significant difference were found in clinical success rate [OR 1.04, 95%CI (0.35,3.07)] and radiographic success rate [OR 0.71, 95%CI (0.37,1.35)] at 12 month follow-up also. Comparison of LASER with Ferric Sulphate also did not show a statistically significant difference.
Meta-analysis showed no statistically significant difference in clinical and radiographic outcomes of LASER pulpotomy with conventional pulpotomy (formocresol and ferric sulphate) at 6 and 12 months follow-up. However, there was considerable risk of bias in the included studies. Pulp therapy, Laser, formocresol.
基于临床和影像学结果,系统评价激光在乳牙活髓切断术中相对于传统治疗方法的有效性。
本系统评价和荟萃分析纳入了比较激光与传统活髓切断术治疗方法(甲醛甲酚、硫酸铁、矿物三氧化物凝聚体或氢氧化钙)的随机或半随机试验,随访期至少为6个月。评估纳入研究的偏倚风险,并使用RevMan软件进行荟萃分析。
在检索的1383篇文章中,仅14项研究纳入定性分析,10项纳入荟萃分析。在乳牙活髓切断术6个月时,与甲醛甲酚相比,激光治疗的临床成功率[比值比(OR)0.99,95%置信区间(CI)(0.19,5.22)]或影像学成功率[OR 0.77,95%CI(0.31,1.87)]无统计学显著差异。在12个月随访时,临床成功率[OR 1.04,95%CI(0.35,3.07)]和影像学成功率[OR 0.71,95%CI(0.37,1.35)]也无统计学显著差异。激光与硫酸铁的比较也未显示统计学显著差异。
荟萃分析表明,在6个月和12个月随访时,激光活髓切断术与传统活髓切断术(甲醛甲酚和硫酸铁)在临床和影像学结果上无统计学显著差异。然而,纳入研究存在相当大的偏倚风险。牙髓治疗、激光、甲醛甲酚。