Hoseinkhani Zohreh, Norooznezhad Fathemeh, Rastegari-Pouyani Mohsen, Mansouri Kamran
Medical Biology Research Center Medical Sciences, Health Technology Institute, Kermanshah, Iran.
Student Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Adv Pharm Bull. 2020 Jul;10(3):370-378. doi: 10.34172/apb.2020.045. Epub 2020 May 11.
Angiogenesis is a strictly controlled process defined as the formation of new blood vessels essential for certain physiologic and pathologic conditions where the latter includes tumor growth, development, and metastasis. Thus, inhibiting angiogenesis along with other anticancer strategies such as chemotherapy seems to be invaluable for reaching an optimal outcome in cancer patients. It has been shown that some natural plant-derived compounds are capable of preventing the formation of these new blood vessels in the tumor and also inhibit the proliferation and growth of the cancer cells. In this review, we intend to introduce plants with anti-angiogenic properties and discuss their related features.
血管生成是一个受到严格调控的过程，被定义为形成新的血管，这对于某些生理和病理状况至关重要，其中病理状况包括肿瘤的生长、发展和转移。因此，与化疗等其他抗癌策略一起抑制血管生成，对于癌症患者实现最佳治疗效果似乎具有重要价值。已经表明，一些天然植物衍生化合物能够阻止肿瘤中这些新血管的形成，还能抑制癌细胞的增殖和生长。在这篇综述中，我们打算介绍具有抗血管生成特性的植物并讨论它们的相关特征。
