Bhavsar Vishal, Sanyal Jyoti, Patel Rashmi, Shetty Hitesh, Velupillai Sumithra, Stewart Robert, Broadbent Matthew, MacCabe James H, Das-Munshi Jayati, Howard Louise M
Section of Women's Mental Health, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Clinical Informatics, BRC Nucleus, South London and Maudsley NHS Foundation Trust, UK.
BJPsych Open. 2020 Jul 16;6(4):e73. doi: 10.1192/bjo.2020.52.
How neighbourhood characteristics affect the physical safety of people with mental illness is unclear.
To examine neighbourhood effects on physical victimisation towards people using mental health services.
We developed and evaluated a machine-learning-derived free-text-based natural language processing (NLP) algorithm to ascertain clinical text referring to physical victimisation. This was applied to records on all patients attending National Health Service mental health services in Southeast London. Sociodemographic and clinical data, and diagnostic information on use of acute hospital care (from Hospital Episode Statistics, linked to Clinical Record Interactive Search), were collected in this group, defined as 'cases' and concurrently sampled controls. Multilevel logistic regression models estimated associations (odds ratios, ORs) between neighbourhood-level fragmentation, crime, income deprivation, and population density and physical victimisation.
Based on a human-rated gold standard, the NLP algorithm had a positive predictive value of 0.92 and sensitivity of 0.98 for (clinically recorded) physical victimisation. A 1 s.d. increase in neighbourhood crime was accompanied by a 7% increase in odds of physical victimisation in women and an 13% increase in men (adjusted OR (aOR) for women: 1.07, 95% CI 1.01-1.14, aOR for men: 1.13, 95% CI 1.06-1.21, P for gender interaction, 0.218). Although small, adjusted associations for neighbourhood fragmentation appeared greater in magnitude for women (aOR = 1.05, 95% CI 1.01-1.11) than men, where this association was not statistically significant (aOR = 1.00, 95% CI 0.95-1.04, P for gender interaction, 0.096). Neighbourhood income deprivation was associated with victimisation in men and women with similar magnitudes of association.
Neighbourhood factors influencing safety, as well as individual characteristics including gender, may be relevant to understanding pathways to physical victimisation towards people with mental illness.
社区特征如何影响精神疾病患者的人身安全尚不清楚。
研究社区对使用精神卫生服务者遭受身体伤害的影响。
我们开发并评估了一种基于机器学习的、源自自由文本的自然语言处理(NLP)算法,以确定提及身体伤害的临床文本。该算法应用于伦敦东南部所有接受国民保健服务精神卫生服务的患者记录。收集了该组(定义为“病例”)及同时抽取的对照的社会人口统计学和临床数据,以及急性医院护理使用情况的诊断信息(来自医院事件统计数据,并与临床记录交互式搜索相关联)。多水平逻辑回归模型估计了社区层面的破碎化、犯罪、收入剥夺和人口密度与身体伤害之间的关联(比值比,OR)。
基于人工评定的金标准,NLP算法对(临床记录的)身体伤害的阳性预测值为0.92,敏感性为0.98。社区犯罪每增加1个标准差,女性遭受身体伤害的几率增加7%,男性增加13%(女性的调整后OR(aOR):1.07,95%CI 1.01 - 1.14,男性的aOR:1.13,95%CI 1.06 - 1.21,性别交互作用的P值为0.218)。尽管社区破碎化的调整关联较小,但女性的关联幅度似乎大于男性(aOR = 1.05,95%CI 1.01 - 1.11),而男性的这种关联无统计学意义(aOR = 1.00,95%CI 0.95 - 1.04,性别交互作用的P值为0.096)。社区收入剥夺与男性和女性的伤害存在相似幅度的关联。
影响安全的社区因素以及包括性别在内的个体特征,可能与理解精神疾病患者遭受身体伤害的途径相关。