Li Q
Department of Pathology, Fourth Military Medical College, Xian.
Zhonghua Zhong Liu Za Zhi. 1988 Nov;10(6):427-9.
GFAP is a specific antigen of glial element, but Alpha-1-antichymotrypsin has not been reported in the literature Alpha-1-antichymotrypsin was guided by GFAP using PAP method to the astrocytes of 137 gliomas. 120 (87%) gliomas were positive for Alpha-1-antichymotrypsin. Of these 120 gliomas, 86 (72%) gave diffuse distribution, 17 (14%) gave focal distribution, and 17 (14%) gave scattered distributions. Alpha-1-antichymotrypsin in glioma tissue may be an important tumor marker for diagnosis.
胶质纤维酸性蛋白（GFAP）是神经胶质成分的一种特异性抗原，但文献中尚未报道α1-抗糜蛋白酶。采用PAP法以GFAP为导向，对137例神经胶质瘤的星形胶质细胞检测α1-抗糜蛋白酶。120例（87%）神经胶质瘤α1-抗糜蛋白酶呈阳性。在这120例神经胶质瘤中，86例（72%）呈弥漫性分布，17例（14%）呈局灶性分布，17例（14%）呈散在性分布。神经胶质瘤组织中的α1-抗糜蛋白酶可能是诊断的一项重要肿瘤标志物。
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