Gunaydin Serdar, Ozisik Kanat, Gunertem Orhan Eren, Budak Ali Baran, Babaroglu Seyhan, Tekeli Atike, McCusker Kevin
Department of Cardiac Surgery, Numune Training & Research Hospital, Ankara, Turkey; and Department of Cardiac Surgery, New York Medical College, Valhalla, New York.
J Extra Corpor Technol. 2020 Jun;52(2):90-95. doi: 10.1182/ject-2000015.
We present our multidisciplinary and multistep strategy in patients undergoing minimally invasive aortic valve replacement (mAVR) on minimally invasive extracorporeal circulation (MiECC) compared with control groups of a single strategy and conventional techniques. This cohort study included high-risk patients (Society of Thoracic Surgeons [STS] risk score >8%) undergoing aortic valve surgery under different strategies during the period from January 2017 until March 2019. Patients were matched for age, gender, body mass index, and STS score: group 1 (MiAVR) based on a minimally invasive technique with J-mini-sternotomy, rapid deployment valve (RDV), and type IV customized MiECC; group 2 (control-mAVR) consisted of minimally invasive technique with only J mini-sternotomy and RDV on a conventional extracorporeal system; group 3 (control-MiECC): full sternotomy and type IV customized MiECC; and group 4 (control): full sternotomy on a conventional extracorporeal system. The MiAVR group had significantly less duration of x-clamp time 35.4 ± 11 minutes), postoperative respiratory support (4.1 ± 1 hour), postoperative hemorrhage (250 ± 50 mL), and intensive care unit stay (1 ± .5 days) than the control-conventional (group 4) group. Seventy-six percent of patients did not receive any blood products in MiAVR ( = .025 vs. group 4). Incidence of atrial fibrillation (8%) and low cardiac output (14%) in MiAVR were significantly better than control. Critics of minimally invasive techniques sustain that potential advantages are offset by a longer cross-clamp and cardiopulmonary bypass duration, which may translate into inferior clinical outcomes. We advocate that our multidisciplinary approach supported by multiple technologies may be associated with faster recovery and superior outcomes than conventional minimally/conventional techniques.
我们展示了在接受微创体外循环(MiECC)下微创主动脉瓣置换术(mAVR)的患者中采用的多学科、多步骤策略,并与单一策略和传统技术的对照组进行比较。这项队列研究纳入了2017年1月至2019年3月期间在不同策略下接受主动脉瓣手术的高危患者(胸外科医师协会[STS]风险评分>8%)。患者按年龄、性别、体重指数和STS评分进行匹配:第1组(MiAVR)基于采用J型小切口胸骨切开术、快速部署瓣膜(RDV)和IV型定制MiECC的微创技术;第2组(对照-mAVR)由仅在传统体外循环系统上采用J型小切口胸骨切开术和RDV的微创技术组成;第3组(对照-MiECC):全胸骨切开术和IV型定制MiECC;第4组(对照):在传统体外循环系统上进行全胸骨切开术。与传统对照组(第4组)相比,MiAVR组的主动脉阻断时间明显更短(35.4±11分钟)、术后呼吸支持时间(4.1±1小时)、术后出血量(250±50毫升)和重症监护病房停留时间(1±0.5天)。在MiAVR组中,76%的患者未接受任何血液制品(与第4组相比,P = 0.025)。MiAVR组的心房颤动发生率(8%)和低心排血量发生率(14%)明显优于对照组。微创技术的批评者认为,潜在优势被更长的主动脉阻断和体外循环时间所抵消,这可能导致较差的临床结果。我们主张,我们由多种技术支持的多学科方法可能比传统的微创/传统技术带来更快的恢复和更好的结果。