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急性食管坏死:一例罕见的糖尿病酮症酸中毒所致上消化道出血病例。

Acute esophageal necrosis: A rare case of upper gastrointestinal bleeding from diabetic ketoacidosis.

作者信息

Uhlenhopp Dustin J, Pagnotta Gregory, Sunkara Tagore

机构信息

Department of Internal Medicine.

Department of Gastroenterology and Hepatology, MercyOne Des Moines Medical Center, Des Moines, IA, USA.

出版信息

Clin Pract. 2020 Jun 29;10(2):1254. doi: 10.4081/cp.2020.1254. eCollection 2020 May 19.

Abstract

Acute esophageal necrosis, also known as black esophagus or acute necrotizing esophagitis is a rare condition with roughly 154 cases reported in the literature. This condition is classically diagnosed on its endoscopic findings of a circumferentially black esophagus that abruptly ends at the gastroesophageal junction and transitions to normal gastric mucosa. When present, acute esophageal necrosis potentially signifies a poor prognosis with an overall mortality up to 36%. This case report describes a critically ill patient with multiple comorbidities that was found to have acute esophageal necrosis the entire length of the esophagus secondary to ischemia/hypoperfusion that was caused by diabetic ketoacidosis. The patient had a prolonged hospitalization but was ultimately discharged in stable condition. We also review the literature of this rare esophageal condition.

摘要

急性食管坏死,也称为黑色食管或急性坏死性食管炎,是一种罕见疾病,文献中报道的病例约有154例。这种疾病的典型诊断依据是内镜检查发现食管呈环形黑色,在胃食管交界处突然终止并过渡到正常胃黏膜。一旦出现急性食管坏死,可能预示预后不良,总体死亡率高达36%。本病例报告描述了一名患有多种合并症的重症患者,该患者被发现因糖尿病酮症酸中毒导致的缺血/低灌注,食管全长出现急性食管坏死。患者住院时间延长,但最终病情稳定出院。我们还回顾了关于这种罕见食管疾病的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e9e/7348660/dfdc89e8f672/cp-10-2-1254-g001.jpg

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