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“黑色食管”或古尔维茨综合征:糖尿病酮症酸中毒中上消化道出血的罕见原因。

"Black Esophagus" or Gurvits Syndrome: A Rare Cause of Upper Gastrointestinal Bleeding in Diabetic Ketoacidosis.

作者信息

Jaber Fouad, Alsakarneh Saqr, Sripada Sruthi, Gaur Rishabh, Rajab Rawan, Mohamed Islam, Sanders Kimberly, Ghoz Hassan

机构信息

Internal Medicine, University of Missouri Kansas City, Kansas, USA.

Gastroenterology and Hepatology, University of Missouri Kansas City, Kansas, USA.

出版信息

Cureus. 2023 Feb 14;15(2):e34989. doi: 10.7759/cureus.34989. eCollection 2023 Feb.

DOI:10.7759/cureus.34989
PMID:36938273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10019910/
Abstract

Black esophagus, also called Gurvits syndrome or acute esophageal necrosis (AEN), is a rare, life-threatening condition characterized by necrosis of the esophageal mucosa. We present a 36-year-old man who presented with hematemesis and was admitted for diabetic ketoacidosis (DKA) management. He then had a further episode of hematemesis with hemodynamic instability. The esophagogastroduodenoscopy (EGD) revealed ulcerative, necrotizing, circumferential esophagitis in the middle and distal third of the esophagus. The patient was treated with intravenous fluid resuscitation, proton pump inhibitors, empiric antibiotics, and antifungals. Hematemesis in DKA should raise suspicion for black esophagus. Prompt detection of AEN allows for early management and thus reduces mortality and associated complications such as perforations and strictures.

摘要

黑色食管,也称为古尔维茨综合征或急性食管坏死(AEN),是一种罕见的、危及生命的疾病,其特征为食管黏膜坏死。我们报告一名36岁男性,因呕血就诊,因糖尿病酮症酸中毒(DKA)管理入院。随后他再次出现呕血并伴有血流动力学不稳定。食管胃十二指肠镜检查(EGD)显示食管中下段溃疡性、坏死性、环形食管炎。该患者接受了静脉补液复苏、质子泵抑制剂、经验性抗生素和抗真菌药物治疗。DKA患者出现呕血应怀疑黑色食管。及时发现AEN可实现早期管理,从而降低死亡率以及穿孔和狭窄等相关并发症的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78fb/10019910/5e7811e68b1e/cureus-0015-00000034989-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78fb/10019910/5e7811e68b1e/cureus-0015-00000034989-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78fb/10019910/5e7811e68b1e/cureus-0015-00000034989-i01.jpg

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本文引用的文献

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Gurvits syndrome: a case of acute esophageal necrosis associated with diabetic ketoacidosis.古维茨综合征:一例与糖尿病酮症酸中毒相关的急性食管坏死。
BMC Gastroenterol. 2022 Jun 2;22(1):277. doi: 10.1186/s12876-022-02349-z.
2
Acute esophageal necrosis complicating diabetic ketoacidosis in a patient with type II diabetes mellitus and excessive cola consumption: a case report.一名患有II型糖尿病且过量饮用可乐的患者,糖尿病酮症酸中毒并发急性食管坏死:病例报告
Diabetol Int. 2021 Aug 27;13(1):315-319. doi: 10.1007/s13340-021-00537-y. eCollection 2022 Jan.
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Acute esophageal necrosis as a complication of diabetic ketoacidosis: A case report.
急性食管坏死作为糖尿病患者代谢性酸中毒的罕见并发症:病例报告。
Am J Case Rep. 2023 Aug 15;24:e939624. doi: 10.12659/AJCR.939624.
急性食管坏死作为糖尿病酮症酸中毒的并发症:一例报告。
World J Clin Cases. 2021 Nov 6;9(31):9571-9576. doi: 10.12998/wjcc.v9.i31.9571.
4
Acute esophageal necrosis: A rare case of upper gastrointestinal bleeding from diabetic ketoacidosis.急性食管坏死:一例罕见的糖尿病酮症酸中毒所致上消化道出血病例。
Clin Pract. 2020 Jun 29;10(2):1254. doi: 10.4081/cp.2020.1254. eCollection 2020 May 19.
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Acute Esophageal Necrosis (Gurvits Syndrome): A Rare Complication of Diabetic Ketoacidosis in a Critically Ill Patient.急性食管坏死(古尔维茨综合征):危重症患者糖尿病酮症酸中毒的一种罕见并发症。
Case Rep Med. 2020 Feb 27;2020:5795847. doi: 10.1155/2020/5795847. eCollection 2020.
6
A Dire Presentation of Diabetic Ketoacidosis with "Black Esophagus.伴有“黑色食管”的糖尿病酮症酸中毒的严重表现
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Black Esophagus (Acute Necrotizing Esophagitis) and Wischnewsky Lesions in a Death From Diabetic Ketoacidosis: A Possible Underlying Mechanism.黑食管(急性坏死性食管炎)和 Wischnewsky 病变在糖尿病酮症酸中毒死亡中:一种可能的潜在机制。
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