检测感染根管中的红色复合体细菌（ 、 和 ）及其与临床症状体征的关联。 （注：原文中红色复合体细菌的具体种类未完整列出）
Detection of Red complex bacteria, , and in infected root canals and their association with clinical signs and symptoms.
作者信息
Tiwari Sonia, Saxena Sudhanshu, Kumari Aarti, Chatterjee Silpi, Hazra Adreet, Choudhary Alok Ratan
机构信息
Department of Pediatric and Preventive Dentistry, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India.
Department of Public Health Dentistry, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India.
出版信息
J Family Med Prim Care. 2020 Apr 30;9(4):1915-1920. doi: 10.4103/jfmpc.jfmpc_1177_19. eCollection 2020 Apr.
AIM
This study aimed to investigate the association between endodontic clinical signs and symptoms and the presence of , and employing polymerase chain reaction (PCR).
MATERIALS AND METHODS
Microbial samples were obtained from 60 cases with necrotic pulp with primary teeth infections. DNA extracted from samples were analyzed for endodontic pathogens by using species-specific primers.
RESULTS
were detected in 15 symptomatic teeth associated with periapical lesions. were found in 16 symptomatic teeth associated with pain and swelling. was detected in 9 teeth which were associated with pain, 2 with tenderness on percussion, and 15 with periapical lesions. Statistically significant associations were found between as well as in relation to clinical findings of pain and swelling. ( < 0.05). Red complex bacteria showed no statistical significant association with the presence of signs and symptoms.
CONCLUSION
Prevalence of , , and suggested association of these bacteria with symptomatic infected pulp and periradicular diseases.
目的
本研究旨在通过聚合酶链反应（PCR）调查牙髓病临床体征和症状与[具体细菌名称1]、[具体细菌名称2]及[具体细菌名称3]存在之间的关联。
材料与方法
从60例患有乳牙感染性牙髓坏死的病例中获取微生物样本。使用种特异性引物对从样本中提取的DNA进行牙髓病病原体分析。
结果
在15颗伴有根尖周病变的有症状牙齿中检测到[具体细菌名称1]。在16颗伴有疼痛和肿胀的有症状牙齿中发现[具体细菌名称2]。在9颗伴有疼痛、2颗叩诊有压痛以及15颗伴有根尖周病变的牙齿中检测到[具体细菌名称3]。在疼痛和肿胀的临床发现方面，[具体细菌名称1]以及[具体细菌名称2]之间存在统计学显著关联（P<0.05）。红色复合体细菌与体征和症状的存在无统计学显著关联。
结论
[具体细菌名称1]、[具体细菌名称2]及[具体细菌名称3]的流行表明这些细菌与有症状的感染牙髓及根尖周疾病有关联。
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