Khochtali Sana, Dridi Tarek, Abroug Nesrine, Ksiaa Imen, Lupidi Marco, Khairallah Moncef
Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.
Section of Ophthalmology, Department of Surgical and Biomedical Sciences, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.
J Curr Ophthalmol. 2020 Apr 30;32(2):211-215. doi: 10.4103/JOCO.JOCO_107_20. eCollection 2020 Apr-Jun.
To report two cases of typical multiple evanescent white dot syndrome (MEWDS), in which swept-source optical coherence tomography angiography (SS-OCTA) revealed transient areas of flow deficit at the level of the choriocapillaris.
The SS-OCTA images of two female patients with typical MEWDS were analyzed at the onset of the disease and during follow-up.
The patients were aged 24 and 25 years, respectively. Previous medical history was unremarkable in both cases. The diagnosis of MEWDS was made on the basis of typical clinical findings and results of fundus autofluorescence, fluorescein angiography, and optical coherence tomography. At presentation, SS-OCTA showed a few small hypointense areas of flow deficit at the level of the choriocapillaris in both cases. During follow-up, SS-OCTA showed complete resolution of choriocapillaris flow voids.
Both our patients with typical acute MEWDS showed SS-OCTA multifocal small areas of flow reduction at the level of the choriocapillaris, with full recovery during the follow-up. This finding supports the hypothesis of transient, primary, or secondary choriocapillaris hypoperfusion in typical MEWDS.
报告两例典型的多发性一过性白点综合征（MEWDS），其中扫频源光学相干断层扫描血管造影（SS-OCTA）显示脉络膜毛细血管层存在短暂性血流缺失区域。
对两名患有典型MEWDS的女性患者在疾病发作时及随访期间的SS-OCTA图像进行分析。
两名患者年龄分别为24岁和25岁。两例患者既往病史均无明显异常。MEWDS的诊断基于典型的临床表现以及眼底自发荧光、荧光素血管造影和光学相干断层扫描的结果。就诊时，两例患者的SS-OCTA均显示脉络膜毛细血管层有少量小的低信号血流缺失区域。随访期间，SS-OCTA显示脉络膜毛细血管层血流缺失完全消失。
我们的两名典型急性MEWDS患者均显示SS-OCTA在脉络膜毛细血管层有多灶性小面积血流减少，随访期间完全恢复。这一发现支持了典型MEWDS中存在短暂性、原发性或继发性脉络膜毛细血管灌注不足的假说。
