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一只产后母犬因子宫炎和胎盘植入穿透导致子宫穿孔。

Uterine perforation secondary to metritis and placenta percreta in a postpartum bitch.

作者信息

Rosenberg Lacey M, Marinoff Jacqueline, Crouch Esther E, Valenzano Dominick M, Peters-Kennedy Jeanine, Cheong Soon Hon, de Amorim Mariana Diel

机构信息

Department of Clinical Sciences (Rosenberg, Valenzano, Cheong, Diel de Amorim), Department of Biomedical Sciences (Marinoff, Crouch, Peters-Kennedy), College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.

出版信息

Can Vet J. 2020 Jun;61(6):584-588.

PMID:32675809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7236632/
Abstract

A 3-year-old intact female Labradoodle bitch was referred due to fever and lethargy 4 days postpartum. The dog was reported to have had prolonged labor that required assistance and fetal membranes were retained. Physical examination and diagnostics led to a suspicion of metritis and uterine perforation. Ovariohysterectomy was performed. Gross and histopathology findings revealed multifocal uterine perforation, necrosuppurative metritis, and placenta percreta. Post-operative antibiotic therapy and supportive care resulted in an uneventful clinical recovery. This is the first reported case of placenta percreta in a bitch. It is presumed that this pathology was paramount in the patient's development of metritis and subsequent uterine rupture. Key clinical message: Placenta percreta may lead to more severe clinical consequences of metritis, including uterine rupture.

摘要

一只3岁未绝育的雌性拉布拉多贵宾犬混血母犬在产后4天因发热和嗜睡前来就诊。据报告,该犬分娩时间延长,需要助产,且胎膜残留。体格检查和诊断结果怀疑为子宫炎和子宫穿孔。遂进行了卵巢子宫切除术。大体病理和组织病理学检查结果显示多灶性子宫穿孔、坏死性化脓性子宫炎和胎盘植入。术后抗生素治疗和支持性护理使患者临床康复过程顺利。这是首次报道的母犬胎盘植入病例。据推测,这种病理状况在该患者子宫炎及随后子宫破裂的发展过程中起了至关重要的作用。关键临床信息:胎盘植入可能导致子宫炎更严重的临床后果,包括子宫破裂。

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Uterine perforation secondary to metritis and placenta percreta in a postpartum bitch.一只产后母犬因子宫炎和胎盘植入穿透导致子宫穿孔。
Can Vet J. 2020 Jun;61(6):584-588.
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本文引用的文献

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Canine endometrial and vaginal microbiomes reveal distinct and complex ecosystems.犬子宫内膜和阴道微生物组揭示了独特而复杂的生态系统。
PLoS One. 2019 Jan 7;14(1):e0210157. doi: 10.1371/journal.pone.0210157. eCollection 2019.
2
Placenta percreta is associated with more frequent severe maternal morbidity than placenta accreta.胎盘植入比胎盘粘连更常导致严重的产妇发病率。
Am J Obstet Gynecol. 2018 Aug;219(2):193.e1-193.e9. doi: 10.1016/j.ajog.2018.04.049. Epub 2018 May 5.
3
Periparturient Diseases in the Dam.母畜围产期疾病
Vet Clin North Am Small Anim Pract. 2018 Jul;48(4):663-681. doi: 10.1016/j.cvsm.2018.02.010. Epub 2018 Apr 21.
4
Bacteriological findings in the canine uterus during Caesarean section performed due to dystocia and their correlation to puppy mortality at the time of parturition.因难产进行剖腹产时犬子宫的细菌学检查结果及其与分娩时幼犬死亡率的相关性。
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Associations among serum pro- and anti-inflammatory cytokines, metabolic mediators, body condition, and uterine disease in postpartum dairy cows.产后奶牛血清促炎和抗炎细胞因子、代谢介质、体况与子宫疾病之间的关联。
Reprod Biol Endocrinol. 2013 Nov 9;11:103. doi: 10.1186/1477-7827-11-103.
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Incidence and risk factors for placenta accreta/increta/percreta in the UK: a national case-control study.英国胎盘植入/粘连/穿透的发生率及危险因素:一项全国性病例对照研究。
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Bacterial reproductive pathogens of cats and dogs.猫和狗的细菌性生殖病原体。
Vet Clin North Am Small Anim Pract. 2012 May;42(3):561-82, vii. doi: 10.1016/j.cvsm.2012.01.013.
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Placenta accreta.胎盘植入
Am J Obstet Gynecol. 2010 Nov;203(5):430-9. doi: 10.1016/j.ajog.2010.09.013.
9
Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast.胎盘植入的病理生理学:蜕膜和绒毛外滋养层的作用。
Placenta. 2008 Jul;29(7):639-45. doi: 10.1016/j.placenta.2008.04.008. Epub 2008 Jun 2.
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Comparative placentation and animal models: patterns of trophoblast invasion -- a workshop report.比较胎盘形成与动物模型:滋养层细胞侵袭模式——研讨会报告
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