Kopel Jonathan, Brower Gregory L
School of Medicine, Texas Tech University Health Sciences CenterLubbockTexas.
Department of Medical Education, Texas Tech University Health Sciences CenterLubbockTexas.
Proc (Bayl Univ Med Cent). 2020 May 29;33(3):469-470. doi: 10.1080/08998280.2020.1767461. eCollection 2020 Jul.
Herpes zoster or shingles causes a severe painful rash that spreads along dermatomes in the face or chest wall, which leads to a condition known as postherpetic neuralgia (PHN). There is no cure for PHN, but there are many treatments to reduce pain duration and severity. In this case report, we describe a patient treated for PHN using pregabalin (Lyrica) after failure with gabapentin. Despite being listed as a controlled substance by the Food and Drug Administration, pregabalin may be an effective first-line therapy for PHN and other forms of neuropathic and chronic pain.
带状疱疹会引发严重的疼痛性皮疹，皮疹会沿着面部或胸壁的皮节扩散，进而导致一种名为带状疱疹后神经痛（PHN）的病症。目前尚无治愈PHN的方法，但有多种治疗手段可缩短疼痛持续时间并减轻疼痛严重程度。在本病例报告中，我们描述了一名患者，其在加巴喷丁治疗失败后使用普瑞巴林（乐瑞卡）治疗PHN。尽管普瑞巴林被美国食品药品监督管理局列为管制药物，但它可能是治疗PHN及其他形式神经病理性疼痛和慢性疼痛的一种有效一线疗法。
