Whitaker Hayley, Tam Joseph O, Connor Martin J, Grey Alistair
Division of Surgical and Interventional Sciences, Faculty of Medicine, University College London, London, UK.
Imperial Prostate, Division of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
Transl Androl Urol. 2020 Jun;9(3):1481-1491. doi: 10.21037/tau.2019.07.17.
Prostate Cancer is now the second biggest cause of cancer mortality in the UK. Media coverage has been rising, with some attributing to a rise in the cases diagnosed and treated in the NHS down to the "Fry and Turnbull effect". Our understanding of prostate cancer has increased tremendously in the past decades, with advances in molecular biology and genomics driving the way to new treatments and diagnostics. This Special Edition of Translational Andrology and Urology 2019: Prostate Cancer Biology and Genomics aims to review the current state of prostate cancer genomics, proteomics, diagnostics and treatment.
前列腺癌目前是英国癌症死亡的第二大原因。媒体报道一直在增加,一些人将其归因于国民保健制度(NHS)诊断和治疗的病例增加,这要归功于“弗莱和特恩布尔效应”。在过去几十年里,随着分子生物学和基因组学的进展推动了新治疗方法和诊断技术的发展,我们对前列腺癌的认识有了极大提高。《转化男科学与泌尿学2019年特刊:前列腺癌生物学与基因组学》旨在综述前列腺癌基因组学、蛋白质组学、诊断和治疗的现状。