Karatsourakis Theofilos-Diamantis, Baraliakos Xenofon
AbbVie Pharmaceuticals S.A., Athens, Greece.
Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany.
Mediterr J Rheumatol. 2020 May 25;31(Suppl 1):145-151. doi: 10.31138/mjr.31.1.145. eCollection 2020 Jun.
The Treat-To-Target (TTT) approach is an important part of clinical practice in rheumatology. Although this approach is well structured in rheumatoid arthritis (RA) and data are accumulating in psoriatic arthritis (PsA) and axial spondyloarthritides (AxSpA), the systematic application of this process in clinical practice can be further improved to achieve better treatment outcomes.
The aim of this study was to present the perspective of clinical rheumatologists on how they evaluate disease activity, in what patient groups they regularly use treatment targets, and how they prioritize treatment targets in spondyloarthritides.
A questionnaire consisting of eight questions on the management of RA, PsA and AxSpA (4 focusing on the use of indexes when setting treatment targets, 2 on the frequency and the patient groups to which these are being applied, and 2 on the physician's priorities in managing different manifestations of the SpA spectrum) was completed by private practice and hospital-based rheumatologists.
160 rheumatologists completed the questionnaire. The majority use the formal composite indexes in clinical practice, certain items from these indexes, and patients' evaluation of the treatment intervention. Indexes are applied frequently in most patient groups, and the priorities of rheumatologists include both musculoskeletal manifestations, as well as the other clinical aspects of the SpA spectrum.
The results can contribute to the understanding of the adherence of rheumatologists to this TTT strategy.
治疗达标（TTT）方法是风湿病临床实践的重要组成部分。尽管这种方法在类风湿关节炎（RA）中结构完善，且在银屑病关节炎（PsA）和轴性脊柱关节炎（AxSpA）方面的数据也在不断积累，但该过程在临床实践中的系统应用仍可进一步改进，以实现更好的治疗效果。
本研究的目的是呈现临床风湿病学家对于他们如何评估疾病活动度、在哪些患者群体中常规使用治疗目标以及他们如何在脊柱关节炎中对治疗目标进行优先级排序的观点。
一份由关于RA、PsA和AxSpA管理的八个问题组成的问卷（4个问题聚焦于设定治疗目标时指标的使用，2个问题涉及这些指标应用的频率和患者群体，2个问题关于医生在管理SpA谱系不同表现时的优先级）由私人执业和医院的风湿病学家完成。
160名风湿病学家完成了问卷。大多数人在临床实践中使用正式的综合指标、这些指标中的某些项目以及患者对治疗干预的评估。指标在大多数患者群体中频繁应用，风湿病学家的优先级既包括肌肉骨骼表现，也包括SpA谱系的其他临床方面。
这些结果有助于理解风湿病学家对这种TTT策略的遵循情况。
