N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation.
Chem Commun (Camb). 2020 Aug 19;56(66):9453-9456. doi: 10.1039/d0cc04617e.
A visible-light-promoted fluoroalkylation-thiolation of alkenes is described. A 4-tetrafluoropyridinylthio fragment serves as a photoredox-active group in the initiation step and undergoes a radical group transfer, which is important for the reaction efficiency. In the primary products, the pyridinylthio substituent may be further functionalized via radical processes or an aromatic substitution reaction.
描述了一种可见光促进的烯烃的氟烷基化-硫代反应。在引发步骤中，一个 4-四氟吡啶基硫基片段充当光氧化还原活性基团，并经历自由基基团转移，这对反应效率很重要。在初级产物中，吡啶基硫取代基可以通过自由基过程或芳构取代反应进一步官能化。
