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评论 Saber 等人（2019 年）的文章“评论：用于评估肺癌风险的大鼠慢性吸入研究可能优于其声誉”。

Comment on Saber et al. (2019), "Commentary: the chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation".

机构信息

Ernest Mario School of Pharmacy, Rutgers, New Brunswick, NY, 07046, USA.

Nanoconsult, Meerssen, Netherlands.

出版信息

Part Fibre Toxicol. 2020 Jul 16;17(1):33. doi: 10.1186/s12989-020-00365-z.

DOI:10.1186/s12989-020-00365-z
PMID:32678050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7367332/
Abstract

In their Commentary Saber et al. (Part Fibre Toxicol 16: 44, 2019) argue that chronic inhalation studies in rats can be used for assessing the lung cancer risk of insoluble nanomaterials. The authors make several significant errors in their interpretation and representation of the underlying science. In this Letter to the Editor we discuss these inaccuracies to correct the scientific record. When the science is recounted accurately it does not support Saber et al's statements and conclusions.

摘要

在他们的评论中，Saber 等人（Part Fibre Toxicol 16: 44, 2019）认为，大鼠的慢性吸入研究可用于评估不溶性纳米材料的肺癌风险。作者在解释和表述基础科学方面存在几个重大错误。在这篇给编辑的信中，我们讨论了这些不准确之处，以纠正科学记录。当科学被准确地叙述时，它并不支持 Saber 等人的陈述和结论。

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Commentary: the chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation.述评：评估肺癌风险的大鼠慢性吸入研究可能比其名声更好。
Part Fibre Toxicol. 2019 Nov 21;16(1):44. doi: 10.1186/s12989-019-0330-4.
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Carbon Black and Lung Cancer Mortality-A Meta-regression Analysis Based on Three Occupational Cohort Studies.炭黑与肺癌死亡率——基于三项职业队列研究的荟萃回归分析。
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