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诊断后体力活动:与老年乳腺癌幸存者长期疲劳和睡眠障碍的关联。

Postdiagnosis Physical Activity: Association With Long-Term Fatigue and Sleep Disturbance in Older Adult Breast Cancer Survivors.

机构信息

University of Washington.

Kaiser Permanente Northern California.

出版信息

Clin J Oncol Nurs. 2020 Aug 1;24(4):381-391. doi: 10.1188/20.CJON.381-391.

Abstract

BACKGROUND

Physical activity is frequently proposed as an intervention to reduce fatigue and sleep disturbance in cancer survivors; however, the long-term effects of physical activity are often not reported, and older adults are typically excluded from these intervention studies.

OBJECTIVES

This article aimed to examine if postdiagnosis physical activity is associated with lower long-term fatigue and sleep disturbance in older adult breast cancer survivors.

METHODS

Data were analyzed of a prospective cohort of 440 breast cancer survivors aged 65 years or older from the Women's Health Initiative study. Multiple linear and logistic regression models were used to examine associations of physical activity with fatigue and sleep disturbance.

FINDINGS

Higher postdiagnosis physical activity was associated with lower long-term fatigue but was not associated with lower sleep disturbance after adjusting for demographics, cancer characteristics, and baseline measures.

摘要

背景

体力活动常被提议作为一种干预措施,以减少癌症幸存者的疲劳和睡眠障碍;然而,体力活动的长期效果通常没有报道,而且老年人通常被排除在这些干预研究之外。

目的

本研究旨在探讨诊断后体力活动是否与老年乳腺癌幸存者的长期疲劳和睡眠障碍程度较低有关。

方法

对妇女健康倡议研究中年龄在 65 岁及以上的 440 名乳腺癌幸存者的前瞻性队列数据进行了分析。采用多元线性和逻辑回归模型来检验体力活动与疲劳和睡眠障碍之间的关联。

发现

在调整人口统计学、癌症特征和基线测量后,较高的诊断后体力活动与较低的长期疲劳相关,但与较低的睡眠障碍无关。

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The pathophysiology of cancer-related fatigue: current controversies.癌症相关性乏力的病理生理学:当前的争议。
Support Care Cancer. 2018 Oct;26(10):3353-3364. doi: 10.1007/s00520-018-4318-7. Epub 2018 Jun 30.

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