Department of Obstetrics and Gynecology and The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Department of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
J Endourol. 2021 Jan;35(1):91-96. doi: 10.1089/end.2020.0618. Epub 2020 Sep 7.
To investigate risk factors associated with urinary tract infection (UTI), following ureteral stenting, for patients with renal colic during pregnancy. Patients with renal colic during pregnancy who underwent ureteral stenting in The First Affiliated Hospital of Guangzhou Medical University between 2009 and 2019 were examined retrospectively. Ureteral stenting patients who had UTIs after hospital discharge and before delivery were classified as the infected group. Multivariate logistic regression analysis was used to assess the risk factors associated with UTI after ureteral stenting. A total of 102 patients were enrolled into the study. Mean age was 30 years (interquartile range [IQR]: 26-33 years) and mean gestation age was 22 weeks (IQR: 18-28 weeks). UTI occurred in 21 patients (20.6%). Compared with noninfected patients, infected patients had a higher rate of positive urine culture (52.4% 13.6%, = 0.000), kidney stones ≥10 mm (81% 35.8%, = 0.000), residual stones after ureteral stenting (71.4% 43.2%, = 0.021), and different surgical indications and gestational ages (18 23 weeks, = 0.00). Multifactor analysis showed that gestational age, positive urine culture (odds ratio [OR] = 6.233, 95% confidence interval [CI]: 1.830-21.227), and stones ≥10 mm (OR = 0.124, 95% CI: 0.031-0.495) were independent risk factors for UTI after ureteral stenting in patients with renal colic. In the infection group, was the most commonly found organism (47.4%). Gestational age, positive urine culture before surgery, and stone ≥10 mm were risk factors for UTI after ureteral stenting in pregnant patients with renal colic. was the main pathogen of UTI after this procedure. Preoperative anti-infection treatment needs to be based on drugs that are sensitive to .
探讨妊娠合并肾绞痛患者留置输尿管支架后发生尿路感染(UTI)的相关危险因素。
回顾性分析 2009 年至 2019 年期间在广州医科大学附属第一医院接受输尿管支架置入术的妊娠合并肾绞痛患者。将出院后至分娩前发生 UTI 的患者归入感染组。采用多因素 logistic 回归分析评估输尿管支架置入术后 UTI 的相关危险因素。
本研究共纳入 102 例患者,平均年龄为 30 岁(四分位距:26-33 岁),平均妊娠周数为 22 周(四分位距:18-28 周)。21 例(20.6%)患者发生 UTI。与非感染组相比,感染组患者的尿液培养阳性率(52.4% vs. 13.6%,=0.000)、结石直径≥10mm 比例(81% vs. 35.8%,=0.000)、留置输尿管支架后残石比例(71.4% vs. 43.2%,=0.021)、不同手术适应证及妊娠周数(18-23 周,=0.00)更高。多因素分析显示,妊娠周数、术前尿液培养阳性(比值比[OR]:6.233,95%置信区间[CI]:1.830-21.227)及结石直径≥10mm(OR:0.124,95%CI:0.031-0.495)是妊娠合并肾绞痛患者留置输尿管支架后发生 UTI 的独立危险因素。在感染组中,最常见的病原体为(47.4%)。妊娠周数、术前尿液培养阳性及结石直径≥10mm 是妊娠合并肾绞痛患者留置输尿管支架后发生 UTI 的危险因素,是该操作后 UTI 的主要病原体。术前抗感染治疗需要根据药敏试验结果选择敏感药物。