Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, U.S.A.
Laryngoscope. 2021 Mar;131(3):686-689. doi: 10.1002/lary.28900. Epub 2020 Jul 18.
To determine the prevalence of sleep disorders in the United States and the association between sleep disorders and all-cause mortality.
A cross-sectional analysis of the 2009 to 2010 National Health and Nutrition Examination Survey (NHANES) and 2015 National Death Index (NDI) was performed. The 2009 to 2010 NHANES national household survey for adults ≥ 18 years was examined for the prevalence of sleep disorders as well as standard demographics and the presence of comorbidities (coronary artery disease [CAD], stroke, and emphysema). This dataset was linked to the 2015 NDI to associate the presence of sleep disorders with 5-year all-cause mortality.
The study sample had a mean age of 46.1 years old, was 48.3% male, and had an average body mass index (BMI) of 28.7 (28.4-28.9). 7.1% (6.5%-7.7%) of adults reported being diagnosed with a sleep disorder, which represents an estimated 15.9 million (13.2-18.6) patients. The estimated mortality rate for those having a sleep disorder was 9.3% (7.2%-11.9%) compared to 5.2% (4.5%-5.9%) without a sleep disorder (odds ratio 1.89, P = <.001). After adjusting for age, sex, BMI, CAD, stroke, and emphysema, having a sleep disorder remained a significant predictor of increased mortality (hazard ratio, 1.5 [1.02-2.18], P = .042).
This study reports a high prevalence of self-reported but physician-diagnosed sleep disorders; however, this likely represents an underestimate. Given the association with all-cause mortality, there is a need for increased recognition of undiagnosed sleep disorders within the United States.
2b Laryngoscope, 131:686-689, 2021.
确定美国睡眠障碍的患病率,以及睡眠障碍与全因死亡率之间的关系。
对 2009 年至 2010 年全国健康和营养调查(NHANES)和 2015 年国家死亡指数(NDI)进行横断面分析。对≥18 岁成年人的 2009 年至 2010 年 NHANES 全国家庭调查进行了睡眠障碍的患病率以及标准人口统计学和合并症(冠心病[CAD]、中风和肺气肿)的检查。该数据集与 2015 年 NDI 相关联,以将睡眠障碍的存在与 5 年全因死亡率联系起来。
研究样本的平均年龄为 46.1 岁,48.3%为男性,平均体重指数(BMI)为 28.7(28.4-28.9)。7.1%(6.5%-7.7%)的成年人报告被诊断患有睡眠障碍,这代表了约 1590 万(13.2-18.6)名患者。患有睡眠障碍的患者的估计死亡率为 9.3%(7.2%-11.9%),而没有睡眠障碍的患者为 5.2%(4.5%-5.9%)(比值比 1.89,P<.001)。在调整年龄、性别、BMI、CAD、中风和肺气肿后,患有睡眠障碍仍然是死亡率增加的显著预测因素(风险比,1.5[1.02-2.18],P=.042)。
本研究报告了自我报告但经医生诊断的睡眠障碍的高患病率;然而,这可能代表了低估。鉴于与全因死亡率的关联,美国需要更多地认识到未确诊的睡眠障碍。
2b 喉镜,131:686-689,2021。