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病例报告:COVID-19 合并双侧肾上腺出血。

Case Report: COVID-19 with Bilateral Adrenal Hemorrhage.

机构信息

1Internal Medicine Department, La Paz University Hospital, Madrid, Spain.

2Endocrinology Department, La Paz University Hospital, Madrid, Spain.

出版信息

Am J Trop Med Hyg. 2020 Sep;103(3):1156-1157. doi: 10.4269/ajtmh.20-0722.

Abstract

A 70-year-old Dominican Republic man presented with lower back pain for 10 days. Fifteen days before pain onset, he had low-grade fever, chills, and asthenia, and 4 days before admission, he had constipation, malaise, generalized weakness, anorexia, nausea, and vomiting. On admission, the patient was afebrile and hypotensive, with a heart rate of 105 and an oxyhemoglobin saturation on room air of 95%. Hyponatremia, lymphopenia, elevated C-reactive protein, and ferritin were observed in complementary tests. Computed tomography (CT) scan showed findings consistent with COVID-19 bilateral bronchopneumonia, and an increase in size and blurring (loss of the Y shape) of both adrenals indicative of acute bilateral adrenal hemorrhage. The patient tested negative by reverse transcription polymerase chain reaction (RT-PCR) of nasopharyngeal swab, yet positive for IgG and IgM by ELISA, suggesting COVID-19 diagnosis.

摘要

一位 70 岁的多米尼加共和国男性因下背部疼痛就诊,病程 10 天。在出现疼痛前 15 天,他有低热、寒战和乏力,在入院前 4 天,他有便秘、不适、全身无力、食欲不振、恶心和呕吐。入院时,患者体温正常且血压低,心率为 105 次/分,室温下血氧饱和度为 95%。补充检查发现低钠血症、淋巴细胞减少、C 反应蛋白和铁蛋白升高。计算机断层扫描(CT)显示符合 COVID-19 双侧支气管肺炎的结果,双侧肾上腺增大和模糊(Y 形消失)提示急性双侧肾上腺出血。患者的鼻咽拭子逆转录聚合酶链反应(RT-PCR)检测结果为阴性,但酶联免疫吸附试验(ELISA)检测 IgG 和 IgM 为阳性,提示 COVID-19 诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1b/7470557/993df1f4855d/tpmd200722f1.jpg

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