Department of Agricultural Engineering and Socio-Economics, Kobe University, Kobe 657-8501 Japan.
Department of Agricultural Engineering and Socio-Economics, Kobe University, Kobe 657-8501 Japan.
Bioresour Technol. 2020 Nov;315:123810. doi: 10.1016/j.biortech.2020.123810. Epub 2020 Jul 10.
This study was aimed to investigate the mechanisms of oxytetracycline (OTC) and chlortetracycline (CTC) inhibition in anaerobic digestion (AD) using four kinetic models. The results showed that the inhibition rate of OTC was faster than CTC at OTC and CTC between 0.04 and 1.28 g/L. Hydrolysis rate constant was linearly and positively correlated with OTC and increased from 0.172 to 0.193 d, 0.164 to 0.179 d and 0.251 to 0.285 d using first-order kinetic, Fitzhugh and Cone models, respectively, while the maximum specific methane production rate was linearly and negatively correlated with CTC and decreased from 0.028 to 0.016 L/gVS. Cone model was found to give the most satisfactory fitting results followed in descending order by first-order kinetic, Fitzhugh and modified Gompertz models. The kinetic modeling of methane yield helped explain the mechanism of OTC and CTC inhibition in the AD process and provided essential information for further process improvement.
本研究旨在使用四种动力学模型探究土霉素（OTC）和金霉素（CTC）对厌氧消化（AD）抑制作用的机制。结果表明，在 0.04 至 1.28 g/L 范围内，OTC 的抑制率快于 CTC。水解速率常数与 OTC 和 CTC 呈线性正相关，使用一级动力学、菲克和 Cone 模型分别从 0.172 增至 0.193 d、0.164 增至 0.179 d 和 0.251 增至 0.285 d，而最大比甲烷生成速率与 CTC 呈线性负相关，从 0.028 降至 0.016 L/gVS。Cone 模型的拟合结果最令人满意，其次是一级动力学、菲克和修正 Gompertz 模型。甲烷产率的动力学建模有助于解释 OTC 和 CTC 在 AD 过程中的抑制机制，并为进一步的工艺改进提供了重要信息。
