Chaiyakulsil Chanapai, Pharadornuwat Onsuthi
Division of Pediatric Critical Care, Department of Pediatrics, Faculty of Medicine, Thammasat University, Prathumthani, Thailand.
Clin Exp Pediatr. 2021 Mar;64(3):123-129. doi: 10.3345/cep.2020.00143. Epub 2020 Jul 14.
The use of indwelling central venous access devices (CVADs) in children can result in complications such as infection, occlusion, and dislodgement.
To evaluate whether reinforcing CVAD care bundles by using a regular direct feedback system could reduce such complications in children.
The intervention in this retrospective interrupted time-series study was initiated in January 2019. The study was divided into the preintervention (October-December 2018), 3-month postintervention (January-March 2019), and 6-month postintervention (April-June 2019) phases. Risk difference and Poisson regression analyses were used to illustrate the effectiveness of the intervention.
The hospital-wide central line-related bloodstream infection rate decreased from 10.0/1,000 catheter-days to 4.5/1,000 catheter-days at 3-month postintervention (P=0.39) and to 1.4/1,000 catheter-days at 6-month postintervention (P=0.047). The central line occlusion rate significantly decreased from 30% to 12.8% (P=0.04) and 8.3% (P=0.002) at 3 and 6 months, respectively. Approximately 7% of CVADs became dislodged during the preintervention phase versus 8.5% (P=0.364) and 3.3% (P=0.378) at 3 and 6 months, respectively.
Reinforcing CVAD care bundles with direct feedback could significantly decrease CVAD-associated complications in terms of infection at 6-month postintervention, and occlusion at 3- and 6-month postintervention. Thus, reinforcement and regular direct feedback might improve care quality in children with CVADs.
在儿童中使用中心静脉置管(CVAD)可能会导致感染、堵塞和移位等并发症。
评估通过使用常规直接反馈系统强化CVAD护理集束是否可以减少儿童的此类并发症。
这项回顾性中断时间序列研究中的干预措施于2019年1月开始。该研究分为干预前阶段(2018年10月至12月)、干预后3个月阶段(2019年1月至3月)和干预后6个月阶段(2019年4月至6月)。采用风险差异和泊松回归分析来说明干预措施的有效性。
在干预后3个月时,全院中心静脉导管相关血流感染率从每1000导管日10.0例降至每1000导管日4.5例(P = 0.39),在干预后6个月时降至每1000导管日1.4例(P = 0.047)。中心静脉导管堵塞率在干预后3个月和6个月时分别从30%显著降至12.8%(P = 0.04)和8.3%(P = 0.002)。在干预前阶段,约7%的CVAD发生移位,而在干预后3个月和6个月时分别为8.5%(P =
0.364)和3.3%(P = 0.378)。
通过直接反馈强化CVAD护理集束可在干预后6个月时显著降低与CVAD相关的感染并发症,并在干预后3个月和6个月时降低堵塞并发症。因此,强化和常规直接反馈可能会提高CVAD患儿的护理质量。