Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, USA.
J Perinatol. 2012 Apr;32(4):281-6. doi: 10.1038/jp.2011.91. Epub 2011 Oct 20.
To determine the association of a central-line maintenance team on the incidence of central-line-associated bloodstream infections (CLABSIs) in the neonatal intensive care unit (NICU).
Central line maintenance in the NICU was limited to a line team starting in March 2008. CLABSI rates were determined before (December 2006 to February 2008) and after implementation of the line team ( March 2008 to August 2010) utilizing consistent National Healthcare Safety Network definitions. Rates were calculated by birth weight categories and overall. Data analysis was performed by two-proportion t test using Minitab.
Overall CLABSI decreased by 65% after implementation of the line team. Pre intervention, mean overall CLABSI rate was 11.6 /1000, as compared with 4.0/1000 after intervention (P<0.001). Birth-weight-specific CLABSI rates also decreased significantly. Decreased infection rates were sustained over time.
A line team provided for standardized, consistent central-line maintenance care leading to a significant, sustained decrease in CLABSI in a NICU.
确定中央导管维护团队对新生儿重症监护病房（NICU）中中心导管相关血流感染（CLABSI）发生率的影响。
自 2008 年 3 月起，NICU 中的中央导管维护仅限于导管团队。在实施导管团队之前（2006 年 12 月至 2008 年 2 月）和之后（2008 年 3 月至 2010 年 8 月），利用国家医疗保健安全网络的一致定义确定 CLABSI 发生率。根据出生体重类别和总体计算发生率。使用 Minitab 通过双样本 t 检验进行数据分析。
实施导管团队后，总体 CLABSI 降低了 65%。干预前，总体 CLABSI 发生率平均为 11.6/1000，而干预后为 4.0/1000（P<0.001）。特定出生体重的 CLABSI 发生率也显著降低。感染率随时间持续下降。
导管团队提供了标准化、一致的中央导管维护护理，导致 NICU 中 CLABSI 的显著、持续下降。
