Chen Hongwu, Chan Kit, Po Sunny S, Chen Minglong
Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Division of Cardiology, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Arrhythm Electrophysiol Rev. 2020 Feb 12;8(4):249-254. doi: 10.15420/aer.2019.07.
Ventricular tachycardias originating from the Purkinje system are the most common type of idiopathic left ventricular tachycardia. The majority if not all of the reentrant circuit involved in this type of tachycardia is formed by the Purkinje fibres of the left bundle branch, particularly the left posterior fascicle. In general, slowly conducting Purkinje fibres (P1) form the antegrade limb, and normally conducting Purkinje fibres (P2) form the retrograde limb of the reentrant circuit of the ventricular tachycardia originating from the left posterior fascicle. Elimination of the critical Purkinje elements in the reentrant circuit is the route to successful ablation. While the reentrant circuit identified by activation mapping provides the roadmap to ablation targets, comparing the difference in the His-ventricular interval during sinus rhythm and tachycardia also helps to identify the critical site in the reentrant circuit.
起源于浦肯野系统的室性心动过速是特发性左室性心动过速最常见的类型。这种类型的心动过速所涉及的折返环大部分(如果不是全部的话)由左束支的浦肯野纤维形成,尤其是左后分支。一般来说,传导缓慢的浦肯野纤维(P1)形成前向支,而传导正常的浦肯野纤维(P2)形成起源于左后分支的室性心动过速折返环的逆向支。消除折返环中关键的浦肯野成分是成功消融的途径。虽然通过激动标测确定的折返环为消融靶点提供了路线图,但比较窦性心律和心动过速期间希氏束 - 心室间期的差异也有助于识别折返环中的关键部位。