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高密度三维标测在儿童患者维拉帕米敏感左后间隔部室性心动过速中的疗效。

Efficacy of High-Density Three-Dimensional Mapping for Verapamil-Sensitive Left Posterior Fascicular Ventricular Tachycardia in Pediatric Patients.

机构信息

Department of Pediatrics, Toyama Prefectural Central Hospital, 2-2-78 Nishinagae-Cho, Toyama-Shi, Toyama, 930-8550, Japan.

Department of Cardiology, Toyama Prefectural Central Hospital, Toyama, Japan.

出版信息

Pediatr Cardiol. 2024 Feb;45(2):368-376. doi: 10.1007/s00246-023-03352-1. Epub 2023 Dec 9.

Abstract

In verapamil-sensitive left posterior fascicular ventricular tachycardia (LPF-VT), radiofrequency catheter ablation (RFA) is performed targeting mid-to-late diastolic potential (P1) and presystolic potential (P2) during tachycardia. This study included four patients who had undergone electrophysiological study (EPS) and pediatric patients with verapamil-sensitive LPF-VT who had undergone RFA using high-density three-dimensional (3D) mapping. The included patients were 11-14 years old. During EPS, right bundle branch block and superior configuration VT were induced in all patients. VT mapping was performed via the transseptal approach. P1 and P2 during VT were recorded in three of the four patients. All patients initially underwent RFA via the transseptal approach. In three patients, P1 during VT was targeted, and VT was terminated. The lesion size indices in which VT was terminated were 4.6, 4.6, and 4.7. For one patient whose P1 could not be recorded, linear ablation was performed perpendicularly in the area where P2 was recorded during VT. Among the three patients in whom VT was terminated, linear ablation was performed in two to eliminate the ventricular echo beats. In all patients, VT became uninducible in the acute phase and had not recurred 8-24 months after RFA. High-density 3D mapping with an HD Grid Mapping Catheter allows recording of P1 and P2 during VT and may improve the success rate of RFA in pediatric patients with verapamil-sensitive LPF-VT.

摘要

在维拉帕米敏感的左后间隔部室性心动过速(LPF-VT)中,针对心动过速期间的中晚期舒张电位(P1)和收缩前期电位(P2)进行射频导管消融(RFA)。本研究纳入了 4 名接受电生理研究(EPS)和 RFA 的维拉帕米敏感的 LPF-VT 儿科患者,他们使用高密度三维(3D)标测。纳入的患者年龄为 11-14 岁。在 EPS 中,所有患者均诱发右束支传导阻滞和优势型 VT。通过经间隔途径进行 VT 标测。在 4 名患者中的 3 名中记录了 VT 期间的 P1 和 P2。所有患者最初均通过经间隔途径进行 RFA。在 3 名患者中,靶向 VT 期间的 P1,终止 VT。终止 VT 的病变大小指数分别为 4.6、4.6 和 4.7。对于 1 名无法记录 P1 的患者,在 VT 期间记录到 P2 的区域进行垂直线性消融。在 VT 终止的 3 名患者中,有 2 名进行了线性消融以消除心室回声。在所有患者中,VT 在急性期变得不可诱导,并且在 RFA 后 8-24 个月内未复发。高密度 3D 标测与 HD Grid Mapping Catheter 结合可记录 VT 期间的 P1 和 P2,并可能提高儿科患者中维拉帕米敏感的 LPF-VT 的 RFA 成功率。

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