Lawrynowicz R
Przegl Dermatol. 1988 Nov-Dec;75(6):439-43.
In a group of 600 patients treated in the Metropolitan Dermatological Hospital in Warsaw bacteriological examination were carried out of swabs from the untreated crural ulcers. In 95% of these cultures growth of pathological aerobic organisms was obtained. Coagulase-positive staphylococci (St. aureus) and Gram-negative bacteria (Pseudomonas aeruginosa, Proteus vulgaris, Enterobacter sp and E. coli) prevailed. In 27% of cases the cultured strains were resistant to the generally available antibiotics. In the second group in 70 patients no growth of anaerobes exclusively was noted. Pathological aerobes and anaerobes in the same case were found in 45% of cultures. In the remaining ones pathogenic aerobes were present with a similar frequency as in the preceding group. Of the anaerobes the most frequently cultured species were Gram-negative bacteria such as Bacteroides melaninogenicus, Bacteroides sp, and Bacteroides fragilis. Among pathogenic anerobic cocci Peptostreptococcus and Peptococcus were most frequent. In 2 cases spore-forming anaerobic bacteria (Clostridium perfringens) were obtained. Forty-eight percent of anaerobes were resistant to the commonly used antibiotics.
在华沙大都会皮肤病医院接受治疗的600名患者中,对未经治疗的小腿溃疡拭子进行了细菌学检查。在这些培养物中,95%获得了致病性需氧菌的生长。凝固酶阳性葡萄球菌(金黄色葡萄球菌)和革兰氏阴性菌(铜绿假单胞菌、普通变形杆菌、肠杆菌属和大肠杆菌)占主导。在27%的病例中,培养的菌株对常用抗生素耐药。在第二组的70名患者中,仅发现厌氧菌无生长。在45%的培养物中发现同一病例中存在致病性需氧菌和厌氧菌。在其余病例中,致病性需氧菌的出现频率与前一组相似。在厌氧菌中,最常培养的菌种是革兰氏阴性菌,如产黑色素拟杆菌、拟杆菌属和脆弱拟杆菌。在致病性厌氧球菌中,消化链球菌和消化球菌最为常见。在2例中获得了产芽孢厌氧菌(产气荚膜梭菌)。48%的厌氧菌对常用抗生素耐药。