Miki H, Hida W, Kikuchi Y, Takishima T
First Department of Internal Medicine, Tohoku University School of Medicine, Sendai Japan.
Tohoku J Exp Med. 1988 Dec;156 Suppl:143-9. doi: 10.1620/tjem.156.suppl_143.
In order to examine the effect of sleep position on sleep apnea episodes, seven male patients diagnosed as having obstructive sleep apnea syndrome without any organic complication of the upper airway were studied while lying in a supine or lateral position during an all-night polysomnographic study. Apnea index, apnea time/total sleep time (%) and the number of episodes per hour in which oxyhemoglobin saturation dropped below 85% decreased significantly from 51.0 +/- 8.6 (mean +/- S.D.) events/hr, 40.4 +/- 5.8% and 36.2 +/- 9.8 episodes/hr during sleep in supine position to 27.6 +/- 9.1 events/hr, 19.4 +/- 6.0% and 12.9 +/- 5.3 episodes/hr during sleep in lateral position, respectively. Lowest oxyhemoglobin saturation increased significantly from 70.7 +/- 2.6% to 78.0 +/- 2.4%. Thus, sleep in the lateral position may be a simple treatment before essential treatment for patients with obstructive sleep apnea syndrome.
为了研究睡眠姿势对睡眠呼吸暂停发作的影响,对7名被诊断为患有阻塞性睡眠呼吸暂停综合征且上呼吸道无任何器质性并发症的男性患者进行了研究,在整夜多导睡眠监测研究中,让他们分别处于仰卧位和侧卧位。呼吸暂停指数、呼吸暂停时间/总睡眠时间(%)以及每小时氧合血红蛋白饱和度降至85%以下的发作次数,在仰卧位睡眠时分别为51.0±8.6(均值±标准差)次/小时、40.4±5.8%和36.2±9.8次/小时,而在侧卧位睡眠时分别显著降至27.6±9.1次/小时、19.4±6.0%和12.9±5.3次/小时。最低氧合血红蛋白饱和度从70.7±2.6%显著升至78.0±2.4%。因此,对于阻塞性睡眠呼吸暂停综合征患者,在进行必要治疗之前,侧卧位睡眠可能是一种简单的治疗方法。