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[一例睡眠呼吸暂停综合征患者,呼吸暂停指数随睡眠体位显著改变]

[A case of sleep apnea syndrome with significant alteration of apnea index by sleep position].

作者信息

Shinozaki S, Matsuzawa Y, Suzawa K, Yamaguchi S, Okada K, Hayano T, Yoshikawa S, Fujimoto K, Kobayashi T, Sekiguchi M

机构信息

First Department of Internal Medicine, Shinshu University School of Medicine.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Aug;31(8):1034-9.

PMID:8230882
Abstract

An obese 37-year-old man (130% ideal body weight) was admitted to our hospital with the complaint of excessive daytime sleepiness. During all-night polysomnography, he showed predominantly obstructive sleep apnea and an apnea index (AI) of 57.5, and was diagnosed as having obstructive sleep apnea syndrome (OSAS). However, AI values calculated separately for the time in the supine position (AI-S) and in the lateral decubitus position (AI-L) were 82.4 and 5.9, respectively. Moreover, duration of apnea, lowest SaO2, and the quality of sleep were improved when sleeping in the lateral compared to the supine position. After weight reduction of 7 kg, AI in total decreased to 33.2, although AI-S was 77.3 and AI-L was 3.8. The improvement of AI in total to be due to a relative increase during sleep in the lateral position. These results suggest that in some OSAS patients, the sleep position should be taken into account in assessing the severity of the disease or in evaluating the effects of therapy. This study also suggests the efficacy of sleep position adjustment in the treatment of OSAS.

摘要

一名37岁的肥胖男性(体重为理想体重的130%)因白天过度嗜睡的主诉入住我院。在整夜多导睡眠监测期间,他主要表现为阻塞性睡眠呼吸暂停,呼吸暂停指数(AI)为57.5,被诊断为患有阻塞性睡眠呼吸暂停综合征(OSAS)。然而,分别计算仰卧位(AI-S)和侧卧位(AI-L)时的AI值,分别为82.4和5.9。此外,与仰卧位相比,侧卧位睡眠时呼吸暂停持续时间、最低血氧饱和度(SaO2)和睡眠质量均有所改善。体重减轻7 kg后,总的AI降至33.2,尽管AI-S为77.3,AI-L为3.8。总的AI改善归因于侧卧位睡眠期间的相对增加。这些结果表明,在一些OSAS患者中,评估疾病严重程度或评估治疗效果时应考虑睡眠姿势。本研究还提示了睡眠姿势调整在OSAS治疗中的有效性。

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