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新生儿和婴儿的肺移植:欧洲新生儿科医生和小儿重症监护医生的 ESPNIC 调查。

Lung transplantation in neonates and infants: ESPNIC survey of European neonatologists and pediatric intensivists.

机构信息

Division of Pediatrics and Neonatal Critical Care, "A.Béclère" Medical Centre, Paris Saclay University Hospitals, APHP, Paris, France.

Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris-Saclay University, Paris, France.

出版信息

Eur J Pediatr. 2021 Jan;180(1):295-298. doi: 10.1007/s00431-020-03742-0. Epub 2020 Jul 21.

Abstract

Lung and heart & lung transplantations in neonates and infants are extreme treatments offered for some life-threatening conditions especially in some North-American centers with promising results. These transplantations are rarely performed in Europe, and we set up a continent-based survey to describe the attitude of European neonatologists and pediatric intensivists on the subject and identify the main indications for this transplantation and the obstacles for the realization of a European lung transplantation program.Conclusion: The main indications for lung transplantation program for neonates and infants are represented by congenital disorders, and physicians indicate as main obstacles the donors' availability. European neonatologists and pediatric intensivists are interested to create a European network to overcome this problem and realize a lung transplantation program for neonates and infants. What is Known: • Lung transplantation in neonates and infants seems to slowly increase, and some North-American centers accumulated a relevant experience. What is New: • European neonatologists and pediatric intensivists are interested in creating a European network for a lung transplantation program for neonates and infants. • The main indications for lung transplantation program for neonates and infants are represented by congenital disorders and main obstacle to lung transplantation is the donors' availability.

摘要

新生儿和婴儿的肺和心肺移植是为某些危及生命的情况提供的极端治疗方法,特别是在一些北美的中心,这些中心取得了有希望的结果。这些移植在欧洲很少进行,我们进行了一项基于欧洲大陆的调查,以描述欧洲新生儿科医生和儿科重症监护医生对此的态度,并确定这种移植的主要适应症和实现欧洲肺移植计划的障碍。

结论

新生儿和婴儿肺移植计划的主要适应症是先天性疾病,医生表示主要障碍是供体的可用性。欧洲新生儿科医生和儿科重症监护医生有兴趣建立一个欧洲网络,以克服这一问题,并为新生儿和婴儿实现肺移植计划。

已知

  • 新生儿和婴儿的肺移植似乎在缓慢增加,一些北美的中心积累了相关经验。

新内容

  • 欧洲新生儿科医生和儿科重症监护医生有兴趣为新生儿和婴儿建立一个肺移植计划的欧洲网络。

  • 新生儿和婴儿肺移植计划的主要适应症是先天性疾病,肺移植的主要障碍是供体的可用性。

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