Department of Eating and Weight Disorders, Villa Garda Hospital, Garda (VR), Veneto, Italy.
Int J Eat Disord. 2020 Sep;53(9):1428-1438. doi: 10.1002/eat.23337. Epub 2020 Jul 21.
This study aimed to compare the effectiveness of an intensive treatment based on enhanced cognitive behavioral therapy (CBT-E) in adolescent and adult patients with anorexia nervosa.
A total of 150 consecutive patients (74 adolescents and 81 adults) were admitted to a 20-week intensive CBT-E program (13 weeks of inpatient followed by 7 weeks of day-hospital treatment). All patients had responded poorly to previous outpatient treatments and were assessed at admission, end of treatment (EOT), and 20- and 60-week follow-ups.
About 70% of eligible patients began the program, and more than 85% completed it. Body mass index (BMI) in adults and BMI-for-age percentile in adolescents improved significantly from baseline to EOT, remained stable until 20-week follow-up, and slightly decreased from 20-week follow-up to 60-week follow-up, while remaining in the lower normal range. Eating disorder psychopathology, general psychopathology, and clinical impairment scores decreased significantly at EOT and showed only a slight increase from EOT to follow-ups. No difference was found between adolescent and adult patients in treatment acceptance, dropout, or any outcome measure.
These findings indicate that intensive CBT-E seems to be an effective treatment for severely ill adolescent and adult patients with anorexia nervosa.
本研究旨在比较强化认知行为疗法（CBT-E）对青少年和成年厌食症患者的疗效。
共有 150 名连续患者（74 名青少年和 81 名成年人）接受了 20 周的强化 CBT-E 方案（13 周住院治疗，随后 7 周日间医院治疗）。所有患者均对先前的门诊治疗反应不佳，并在入院时、治疗结束时（EOT）以及 20 周和 60 周随访时进行评估。
约 70%符合条件的患者开始了该项目，超过 85%的患者完成了该项目。成年人的体重指数（BMI）和青少年的 BMI 年龄百分位数从基线到 EOT 显著改善，在 20 周随访时保持稳定，从 20 周随访到 60 周随访时略有下降，但仍处于较低的正常范围。饮食失调心理病理学、一般心理病理学和临床损伤评分在 EOT 时显著下降，仅从 EOT 到随访时略有增加。在治疗接受率、辍学率或任何结果衡量标准方面，青少年和成年患者之间没有差异。
这些发现表明，强化 CBT-E 似乎是一种有效的治疗方法，适用于患有严重厌食症的青少年和成年患者。
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