Department of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo 89, 37016 Garda, VR, Italy.
Int J Environ Res Public Health. 2023 Feb 12;20(4):3221. doi: 10.3390/ijerph20043221.
The study aimed to establish the role of weight suppression in a cohort of adolescents with anorexia nervosa treated with intensive enhanced cognitive behavioral therapy (CBT-E). One hundred and twenty-eight adolescent patients with anorexia nervosa (128 females and 2 males), aged between 14 and 19 years, were recruited from consecutive referrals to a community-based eating disorder clinic offering intensive CBT-E. Weight, height, Eating Disorder Examination Questionnaire, and Brief Symptom Inventory scores were recorded at admission, end-of-treatment, and at a 20-week follow-up. In addition, the developmental weight suppression (DWS, difference between one's highest premorbid and current z-BMI, i.e., BMI z-scores) was calculated. The mean baseline z-BMI was -4.01 (SD = 2.27), and the mean DWS was 4.2 (SD = 2.3). One hundred and seven patients (83.4%) completed the treatment and showed both considerable weight gain and reduced scores for eating-disorder and general psychopathology. Among completers, 72.9% completed the 20-week follow-up and maintained the improvement reached at the end-of-treatment. DWS was negatively correlated with end-of-treatment and follow-up z-BMI. This indicates that weight suppression is a predictor of the BMI outcome of intensive CBT-E and confirms that this treatment is promising for adolescents with anorexia nervosa.
本研究旨在探讨体重抑制在接受强化认知行为治疗（CBT-E）的青少年厌食症患者队列中的作用。从一家提供强化 CBT-E 的基于社区的饮食失调诊所连续转介的 128 名患有厌食症的青少年患者（128 名女性和 2 名男性），年龄在 14 至 19 岁之间，被招募入组。在入院时、治疗结束时和 20 周随访时记录体重、身高、饮食障碍检查问卷和Brief Symptom Inventory 评分。此外，还计算了发育性体重抑制（DWS，即个体最高前驱体重和当前 z-BMI 之间的差异，即 BMI z 评分）。基线 z-BMI 的平均值为-4.01（SD = 2.27），DWS 的平均值为 4.2（SD = 2.3）。107 名患者（83.4%）完成了治疗，体重明显增加，饮食障碍和一般精神病理学评分降低。在完成治疗的患者中，72.9%完成了 20 周的随访，并维持了治疗结束时达到的改善。DWS 与治疗结束时和随访时的 z-BMI 呈负相关。这表明体重抑制是强化 CBT-E 治疗体重指数结果的预测因素，并证实该治疗对患有厌食症的青少年有希望。
